LINGO1 and SHANK3

  • Number of citations of the paper that reports this interaction (PubMedID 21653829)
  • 98
  • Data Source:
  • BioGRID (two hybrid)

LINGO1

SHANK3

Description leucine rich repeat and Ig domain containing 1 SH3 and multiple ankyrin repeat domains 3
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adult body size ( 32376654)
  • Caffeine consumption from coffee or tea ( 33287642)
  • Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203)
  • Essential tremor ( 19182806)
  • Feeling miserable ( 29500382)
  • General factor of neuroticism ( 30867560)
  • Hemoglobin A1c levels ( 29403010)
  • High density lipoprotein cholesterol levels ( 33339817)
  • Household income (MTAG) ( 31844048)
  • Intelligence (MTAG) ( 29326435)
  • Neuroticism ( 27089181)
  • Risky sexual behaviors (alcohol dependence interaction) ( 28990359)
  • Systemic lupus erythematosus ( 33536424)
  • Triglyceride levels ( 32902719)
Interacting Genes 18 interacting genes: EFEMP2 FBLN1 FBXW7 FRS3 GOLGA2 HSD3B7 KRTAP10-1 KRTAP4-12 KRTAP5-6 KRTAP5-9 KRTAP9-2 MACO1 NGFR NTM RTN4R SHANK3 SPAG5 TRIM27 156 interacting genes: ABCC2 ABI1 ABI2 ACE2 ACTN2 ADGRL1 AGAP7P ALDOA ANKRD35 APP ARHGAP44 ARPC2 ARPC5L ATN1 BAIAP2 C1QBP CA10 CALCOCO1 CAMK2B CCT3 CENPJ CEP72 CIBAR1 CLTA CLU CNKSR2 COPS5 COPS6 COQ5 CRELD1 CRKL CSNK1D CSNK2B CTTN CYP51A1 CYTIP DBNL DCTN2 DDB1 DLGAP1 DLGAP2 DLGAP3 DLGAP4 DNAJA3 DNM2 EFEMP1 EFEMP2 EID1 ELAVL1 ERI3 FAM13A FBXO7 FKBP8 FRS3 FRYL GAPDH GOT1 GPR162 GPS1 GRB2 GRN HAGH HECW1 HGS HNRNPK HOMER3 ICA1 IGSF9 ITGBL1 ITSN1 JAG2 KHDRBS1 KIAA0232 LINGO1 LRRC73 LTBP3 LTBP4 LZTS2 LZTS3 MAPK1 MBIP MBOAT7 MCRS1 MDH2 MEGF10 MEGF11 MEGF6 MIPOL1 MRM3 MT-CO2 MT-ND6 MYO5B N4BP3 NCK1 NCKIPSD NEFL NGRN NOTCH1 NOTCH2 NOTCH2NLA NOTCH3 NR1D1 NRBF2 PAX6 PDHB PFKL PHF12 PHLDB1 PLEKHA4 PPHLN1 PPP1CC PPP1R13L PPP1R9B PPP2R3B PRMT2 QSOX1 RBM5 RPL3 RPS6KA1 RTN3 RUNDC3A SCYL3 SETD2 SH3GL2 SH3GL3 SHANK1 SHARPIN SIPA1 SLC48A1 SNRPN SORBS2 SORBS3 SPAG5 SPTAN1 SRSF9 STK32C SYNGAP1 SYT5 TCF25 TDRD7 TFIP11 THRAP3 TMEM14C TNIP2 TRAF3 TRIM27 TRIM9 TRIP10 TSG101 TUBA1C UCHL1 USP8 VIM VPS18 WWP1 ZCCHC2
Entrez ID 84894 85358
HPRD ID 14322 18979
Ensembl ID ENSG00000169783 ENSG00000251322
Uniprot IDs Q96FE5
PDB IDs 2ID5 4OQT
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?