SHANK3 and MYO5B

  • Number of citations of the paper that reports this interaction (PubMedID 21653829)
  • 98
  • Data Source:
  • BioGRID (two hybrid)

SHANK3

MYO5B

Description SH3 and multiple ankyrin repeat domains 3 myosin VB
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Apolipoprotein A1 levels ( 32203549 29084231)
  • HDL cholesterol levels ( 32203549)
  • Large HDL particle concentration ( 29084231)
  • Mean diameter of HDL particles ( 29084231)
  • Medium HDL particle concentration ( 29084231)
  • Multiple sclerosis ( 31604244)
  • Myopia ( 27182965)
  • Phospholipid levels in large HDL ( 29084231)
  • Phospholipid levels in medium HDL ( 29084231)
  • Refractive error ( 32231278)
  • Resistant hypertension ( 31545351)
  • Spherical equivalent or myopia (age of diagnosis) ( 29808027)
  • Systolic blood pressure x smoking status (current vs non-current) interaction (1df test) ( 29455858)
  • Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858)
  • Total cholesterol levels in HDL ( 29084231)
Interacting Genes 156 interacting genes: ABCC2 ABI1 ABI2 ACE2 ACTN2 ADGRL1 AGAP7P ALDOA ANKRD35 APP ARHGAP44 ARPC2 ARPC5L ATN1 BAIAP2 C1QBP CA10 CALCOCO1 CAMK2B CCT3 CENPJ CEP72 CIBAR1 CLTA CLU CNKSR2 COPS5 COPS6 COQ5 CRELD1 CRKL CSNK1D CSNK2B CTTN CYP51A1 CYTIP DBNL DCTN2 DDB1 DLGAP1 DLGAP2 DLGAP3 DLGAP4 DNAJA3 DNM2 EFEMP1 EFEMP2 EID1 ELAVL1 ERI3 FAM13A FBXO7 FKBP8 FRS3 FRYL GAPDH GOT1 GPR162 GPS1 GRB2 GRN HAGH HECW1 HGS HNRNPK HOMER3 ICA1 IGSF9 ITGBL1 ITSN1 JAG2 KHDRBS1 KIAA0232 LINGO1 LRRC73 LTBP3 LTBP4 LZTS2 LZTS3 MAPK1 MBIP MBOAT7 MCRS1 MDH2 MEGF10 MEGF11 MEGF6 MIPOL1 MRM3 MT-CO2 MT-ND6 MYO5B N4BP3 NCK1 NCKIPSD NEFL NGRN NOTCH1 NOTCH2 NOTCH2NLA NOTCH3 NR1D1 NRBF2 PAX6 PDHB PFKL PHF12 PHLDB1 PLEKHA4 PPHLN1 PPP1CC PPP1R13L PPP1R9B PPP2R3B PRMT2 QSOX1 RBM5 RPL3 RPS6KA1 RTN3 RUNDC3A SCYL3 SETD2 SH3GL2 SH3GL3 SHANK1 SHARPIN SIPA1 SLC48A1 SNRPN SORBS2 SORBS3 SPAG5 SPTAN1 SRSF9 STK32C SYNGAP1 SYT5 TCF25 TDRD7 TFIP11 THRAP3 TMEM14C TNIP2 TRAF3 TRIM27 TRIM9 TRIP10 TSG101 TUBA1C UCHL1 USP8 VIM VPS18 WWP1 ZCCHC2 23 interacting genes: AMOTL2 BNIP2 COIL CXCR2 EFHC2 FAM214B FXR1 GMCL1 KIAA1549 MEI4 MEOX2 POLR1C RAB11A RAB11B RAB11FIP2 RAB25 SHANK3 SMAD3 SMARCA2 TCF4 TRIM3 TRIM54 ZNHIT1
Entrez ID 85358 4645
HPRD ID 18979 07582
Ensembl ID ENSG00000251322 ENSG00000167306
Uniprot IDs Q7Z7A5 Q9ULV0
PDB IDs 4J5M 4LNZ 4LWZ 4LX0
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
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