GEMIN2 and STXBP3

Number of citations of the paper that reports this interaction (PubMedID 12065586)
43

Data Source:
HPRD (in vivo)

		GEMIN2	STXBP3
Description		gem nuclear organelle associated protein 2	syntaxin binding protein 3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex Nucleolus Cytosol Nuclear Body SMN Complex SMN-Sm Protein Complex Gemini Of Coiled Bodies	Cytosol Plasma Membrane Basolateral Plasma Membrane Apical Plasma Membrane Secretory Granule Platelet Alpha Granule Specific Granule Phagocytic Vesicle Extracellular Exosome Tertiary Granule Presynapse
	Molecular Function	Protein Binding	Protein Binding Syntaxin-1 Binding Syntaxin Binding Protein-containing Complex Binding
	Biological Process	Spliceosomal Complex Assembly RNA Splicing, Via Transesterification Reactions Spliceosomal SnRNP Assembly MRNA Processing RNA Splicing Negative Regulation Of RNA Binding	Cellular Glucose Homeostasis Intracellular Protein Transport Vesicle Docking Involved In Exocytosis Neurotransmitter Secretion Brain Development Vesicle-mediated Transport Protein To Membrane Docking Insulin Secretion Response To Insulin Neutrophil Degranulation Negative Regulation Of Calcium Ion-dependent Exocytosis Negative Regulation Of Glucose Import Platelet Aggregation Cellular Response To Interferon-gamma
Pathways		snRNP Assembly	Disinhibition of SNARE formation Translocation of SLC2A4 (GLUT4) to the plasma membrane
Drugs
Diseases
GWAS		Vitamin D levels ( 28757204)	Fat distribution (HIV) ( 21897333)
Interacting Genes		34 interacting genes: AKAP6 BEND7 DDX20 DHX9 FBXO7 GEMIN5 HOXD10 IKBKG INCA1 KPNA6 MEOX1 MTNR1A NUFIP1 PAX6 PSMB1 RN7SL1 RNU1-1 RNU2-1 RPP14 SMN1 SMN2 SNRNP70 SNRPD1 SNRPD2 SNRPD3 SNRPN SPG21 SRSF1 SRSF2 SRSF3 SRSF4 STXBP2 STXBP3 U2AF2	14 interacting genes: DDX20 GEMIN2 GEMIN4 GEMIN5 PRKCA RPL3 SMN1 SNRPB SNRPD2 SNRPD3 SNTG1 STX4 STXBP2 VAMP2
Entrez ID		8487	6814
HPRD ID		03999	10517
Ensembl ID		ENSG00000092208	ENSG00000116266
Uniprot IDs		O14893	O00186
PDB IDs		2LEH 5XJL 5XJQ 5XJR 5XJS 5XJT 5XJU
Enriched GO Terms of Interacting Partners?
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