GEMIN2 and SRSF1

Number of citations of the paper that reports this interaction (PubMedID 9447963)
8

Data Source:
HPRD (two hybrid)

		GEMIN2	SRSF1
Description		gem nuclear organelle associated protein 2	serine and arginine rich splicing factor 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex Nucleolus Cytosol Nuclear Body SMN Complex SMN-Sm Protein Complex Gemini Of Coiled Bodies	Nucleus Nucleoplasm Cytoplasm Nuclear Speck Catalytic Step 2 Spliceosome
	Molecular Function	Protein Binding	RNA Binding MRNA Binding Protein Binding Protein Kinase B Binding DNA Topoisomerase Binding
	Biological Process	Spliceosomal Complex Assembly RNA Splicing, Via Transesterification Reactions Spliceosomal SnRNP Assembly MRNA Processing RNA Splicing Negative Regulation Of RNA Binding	Alternative MRNA Splicing, Via Spliceosome MRNA 5'-splice Site Recognition MRNA Splicing, Via Spliceosome MRNA Splice Site Selection MRNA Processing Positive Regulation Of RNA Splicing Oligodendrocyte Differentiation MRNA Transport Liver Regeneration
Pathways		snRNP Assembly	Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination
Drugs			Copper
Diseases
GWAS		Vitamin D levels ( 28757204)	Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223)
Interacting Genes		34 interacting genes: AKAP6 BEND7 DDX20 DHX9 FBXO7 GEMIN5 HOXD10 IKBKG INCA1 KPNA6 MEOX1 MTNR1A NUFIP1 PAX6 PSMB1 RN7SL1 RNU1-1 RNU2-1 RPP14 SMN1 SMN2 SNRNP70 SNRPD1 SNRPD2 SNRPD3 SNRPN SPG21 SRSF1 SRSF2 SRSF3 SRSF4 STXBP2 STXBP3 U2AF2	42 interacting genes: AKAP17A APP BCL10 C1QBP CACNA1A CD8A CDC42 CDK12 CDK6 CLK1 DANCR DIDO1 DYRK1A GEMIN2 HIPK3 HNRNPA0 LNX1 LUC7L3 NFYA NXF1 PPARG PRPF4 PRPF4B PSIP1 RNPS1 SCAF11 SNRNP70 SREK1 SRPK1 SRPK2 SRSF10 SRSF11 SRSF5 TCERG1 TNPO3 TOP1 TP53 U2AF1 U2AF2 XBP1 YTHDC1 ZRSR2
Entrez ID		8487	6426
HPRD ID		03999	02887
Ensembl ID		ENSG00000092208	ENSG00000136450
Uniprot IDs		O14893	Q07955 Q59FA2
PDB IDs		2LEH 5XJL 5XJQ 5XJR 5XJS 5XJT 5XJU	1X4A 2M7S 2M8D 2O3D 3BEG 4C0O 6HPJ 7ABG
Enriched GO Terms of Interacting Partners?
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