GEMIN2 and SNRNP70

Number of citations of the paper that reports this interaction (PubMedID 9447963)
8

Data Source:
HPRD (in vitro, two hybrid)

		GEMIN2	SNRNP70
Description		gem nuclear organelle associated protein 2	small nuclear ribonucleoprotein U1 subunit 70
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex Nucleolus Cytosol Nuclear Body SMN Complex SMN-Sm Protein Complex Gemini Of Coiled Bodies	Nucleus Nucleoplasm Spliceosomal Complex U1 SnRNP Nuclear Speck U2-type Prespliceosome
	Molecular Function	Protein Binding	RNA Binding MRNA Binding Protein Binding SnRNA Binding U1 SnRNA Binding
	Biological Process	Spliceosomal Complex Assembly RNA Splicing, Via Transesterification Reactions Spliceosomal SnRNP Assembly MRNA Processing RNA Splicing Negative Regulation Of RNA Binding	MRNA Splicing, Via Spliceosome Regulation Of ATPase Activity Regulation Of RNA Splicing Positive Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of Protein Refolding Negative Regulation Of Chaperone-mediated Autophagy
Pathways		snRNP Assembly	mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Vitamin D levels ( 28757204)	Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Systolic blood pressure ( 30224653) Venous thromboembolism ( 33592630)
Interacting Genes		34 interacting genes: AKAP6 BEND7 DDX20 DHX9 FBXO7 GEMIN5 HOXD10 IKBKG INCA1 KPNA6 MEOX1 MTNR1A NUFIP1 PAX6 PSMB1 RN7SL1 RNU1-1 RNU2-1 RPP14 SMN1 SMN2 SNRNP70 SNRPD1 SNRPD2 SNRPD3 SNRPN SPG21 SRSF1 SRSF2 SRSF3 SRSF4 STXBP2 STXBP3 U2AF2	47 interacting genes: APP ARSF CASP3 CDC42 CDKL3 CEP63 CHERP CLK2 CRP CTDP1 DDX17 GEMIN2 GTPBP2 HNRNPA2B1 HTATSF1 IL32 IL7R LRP1 MYC NUDT21 OGT PRKD2 PRMT5 PRPF40A RASGRF1 RELA RNF11 SCAF11 SHBG SKIL SMAD1 SMAD2 SMAD3 SMAD4 SMAD5 SMAD9 SMURF2 SNRPC SRPK1 SRPK2 SRRM4 SRSF1 SRSF10 SRSF2 TOP1 WBP4 ZRANB2
Entrez ID		8487	6625
HPRD ID		03999	01617
Ensembl ID		ENSG00000092208	ENSG00000104852
Uniprot IDs		O14893	A0A024QZD5 P08621 Q9UFS1
PDB IDs		2LEH 5XJL 5XJQ 5XJR 5XJS 5XJT 5XJU	2L5I 2L5J 3CW1 3PGW 4PJO 4PKD 6QX9 7B0Y
Enriched GO Terms of Interacting Partners?
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