DYRK2 and SIAH2

  • Number of citations of the paper that reports this interaction (PubMedID 22878263)
  • 26
  • Data Source:
  • BioGRID (unspecified method)

DYRK2

SIAH2

Description dual specificity tyrosine phosphorylation regulated kinase 2 siah E3 ubiquitin protein ligase 2
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Amyotrophic lateral sclerosis (C9orf72 mutation interaction) ( 22959728)
  • Daytime sleep phenotypes ( 27126917)
  • Itch intensity from mosquito bite ( 28199695)
  • Itch intensity from mosquito bite adjusted by bite size ( 28199695)
  • Malaria ( 31844061)
  • Metabolite levels ( 23823483)
  • Mosquito bite size ( 28199695)
  • Systemic lupus erythematosus ( 28714469)
Interacting Genes 22 interacting genes: APP ATM DYRK4 EIF2B5 H2BC21 H3-4 IKZF1 KATNA1 KXD1 LRRK2 LZTS2 MAPT MDM2 NR1I2 RAD54B SIAH2 SP100 TERT UBE2D1 UBR5 WDR62 ZBTB9 44 interacting genes: AFF1 AKR1C3 ATN1 CACYBP CCBE1 CHEK2 DCC DLST DYRK2 EEF1D EGLN3 HIPK2 HIPK3 MYD88 NRF1 OPRM1 PEG10 PEG3 PIAS2 PIAS3 PML POU2AF1 PSMD4 RBBP8 SETD2 SNCA SNCAIP SPRY2 STAT3 SYP TINF2 TP53BP2 TPX2 TRAF2 UBE2D1 UBE2D2 UBE2D3 UBE2I UBE2L6 UBE2N UBE2V2 USP13 USP19 VAV1
Entrez ID 8445 6478
HPRD ID 04606 03737
Ensembl ID ENSG00000127334 ENSG00000181788
Uniprot IDs Q92630 O43255
PDB IDs 3K2L 3KVW 4AZF 5LXC 5LXD 5ZTN 6HDP 6HDR 6K0J 5H9M
Enriched GO Terms of Interacting Partners?
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