SIAH2 and TPX2

  • Number of citations of the paper that reports this interaction (PubMedID 17716627)
  • 2
  • Data Source:
  • BioGRID (two hybrid, affinity chromatography technology)

SIAH2

TPX2

Description siah E3 ubiquitin protein ligase 2 TPX2 microtubule nucleation factor
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Brain morphology (MOSTest) ( 32665545)
  • Immature fraction of reticulocytes ( 32888494)
  • Mean reticulocyte volume ( 32888494)
  • Monocyte percentage of white cells ( 32888494)
  • Mosaic loss of chromosome Y (Y chromosome dosage) ( 28346444 31624269)
  • Oppositional defiant disorder dimensions in attention-deficit hyperactivity disorder ( 26184070)
  • Prudent dietary pattern ( 28644415)
Interacting Genes 44 interacting genes: AFF1 AKR1C3 ATN1 CACYBP CCBE1 CHEK2 DCC DLST DYRK2 EEF1D EGLN3 HIPK2 HIPK3 MYD88 NRF1 OPRM1 PEG10 PEG3 PIAS2 PIAS3 PML POU2AF1 PSMD4 RBBP8 SETD2 SNCA SNCAIP SPRY2 STAT3 SYP TINF2 TP53BP2 TPX2 TRAF2 UBE2D1 UBE2D2 UBE2D3 UBE2I UBE2L6 UBE2N UBE2V2 USP13 USP19 VAV1 8 interacting genes: AURKA CDK6 GOLGA2 HMMR NAP1L1 SIAH2 SUMO2 THAP11
Entrez ID 6478 22974
HPRD ID 03737 05802
Ensembl ID ENSG00000181788 ENSG00000088325
Uniprot IDs O43255 Q643R0 Q9ULW0
PDB IDs 5H9M 1OL5 3E5A 3HA6 4C3P 5LXM 6BJC 6VPG 6VPH 6VPI 6VPJ 6VPL 6VPM 6XKA
Enriched GO Terms of Interacting Partners?
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