DOT1L and MYCN

  • Number of citations of the paper that reports this interaction (PubMedID 28209620)
  • 27
  • Data Source:
  • BioGRID (affinity chromatography technology, pull down)

DOT1L

MYCN

Description DOT1 like histone lysine methyltransferase MYCN proto-oncogene, bHLH transcription factor
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Asthma or chronic obstructive pulmonary disease ( 24993907)
  • Basal cell carcinoma ( 25855136)
  • Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223)
  • Height ( 31562340)
  • Lymphocyte counts ( 32888494)
  • Metabolite levels ( 23823483)
  • Nonsyndromic cleft lip ( 31609978)
  • Nonsyndromic cleft palate ( 31609978)
  • Pulmonary function (smoking interaction) ( 23284291)
  • Refractive error ( 32231278)
  • Spherical equivalent or myopia (age of diagnosis) ( 29808027)
  • Wilms tumor ( 22544364)
Interacting Genes 4 interacting genes: H3-4 MLLT10 MYCN STAT1 20 interacting genes: CSNK2A1 CSNK2A2 DOT1L EZH2 FBXW7 GRSF1 HUWE1 MAX MXD1 NEDD4 NMI NONO RUNX3 SIRT1 SP1 TRIM32 YAF2 YBX1 YEATS4 ZBTB17
Entrez ID 84444 4613
HPRD ID 10455 01278
Ensembl ID ENSG00000104885 ENSG00000134323
Uniprot IDs Q8TEK3 A0A1W2PPD9 P04198 Q9H224
PDB IDs 1NW3 2MV7 3QOW 3QOX 3SR4 3SX0 3UWP 4EK9 4EKG 4EKI 4EQZ 4ER0 4ER3 4ER5 4ER6 4ER7 4HRA 4WVL 5DRT 5DRY 5DSX 5DT2 5DTM 5DTQ 5DTR 5JUW 5MVS 5MW3 5MW4 6IN3 6J99 6JM9 6JMA 6JN2 6NJ9 6NN6 6NOG 6NQA 6O96 6TE6 6TEL 6TEN 5G1X
Enriched GO Terms of Interacting Partners?
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