RNF135 and CTNNAL1

Number of citations of the paper that reports this interaction (PubMedID 28514442)
406

Data Source:
BioGRID (affinity chromatography technology, two hybrid)

		RNF135	CTNNAL1
Description		ring finger protein 135	catenin alpha like 1
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoplasmic Stress Granule Ribonucleoprotein Complex	Cytosol Cytoskeleton Plasma Membrane
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding RIG-I Binding Identical Protein Binding Ribonucleoprotein Complex Binding Metal Ion Binding Ubiquitin Protein Ligase Activity	Protein Binding Cadherin Binding Actin Filament Binding
	Biological Process	Protein Polyubiquitination Free Ubiquitin Chain Polymerization Protein Ubiquitination Positive Regulation Of Interferon-beta Production RIG-I Signaling Pathway Innate Immune Response Regulation Of Innate Immune Response Protein Homooligomerization Protein K63-linked Ubiquitination Antiviral Innate Immune Response	Cell Adhesion Rho Protein Signal Transduction
Pathways		DDX58/IFIH1-mediated induction of interferon-alpha/beta Ovarian tumor domain proteases TRAF3-dependent IRF activation pathway TRAF6 mediated IRF7 activation TRAF6 mediated NF-kB activation TRAF6 mediated NF-kB activation NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 Negative regulators of DDX58/IFIH1 signaling Negative regulators of DDX58/IFIH1 signaling
Drugs
Diseases
GWAS		Height ( 18391951) Hip circumference adjusted for BMI ( 34021172) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		10 interacting genes: CTBP2 CTNNAL1 DDX58 ENOX2 GOLGA2 HSF2BP IFIH1 TEPSIN UBE2D2 UBE2N	12 interacting genes: AKAP13 BRME1 CALU DMD NEK1 PCGF2 RNF135 SERTAD3 TRIM7 TSC22D4 USH1C ZBED1
Entrez ID		84282	8727
HPRD ID		11506	09210
Ensembl ID		ENSG00000181481	ENSG00000119326
Uniprot IDs		B3KV69 Q8IUD6	B3KMX6 Q9UBT7
PDB IDs		7JL1 7JL3
Enriched GO Terms of Interacting Partners?
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