PIP4K2B and RPRD1B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		PIP4K2B	RPRD1B
Description		phosphatidylinositol-5-phosphate 4-kinase type 2 beta	regulation of nuclear pre-mRNA domain containing 1B
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Autophagosome Endoplasmic Reticulum Membrane Cytosol Plasma Membrane	Nucleus Nucleoplasm RNA Polymerase II, Holoenzyme
	Molecular Function	Protein Binding ATP Binding GTP Binding 1-phosphatidylinositol-4-phosphate 5-kinase Activity 1-phosphatidylinositol-5-phosphate 4-kinase Activity Protein Homodimerization Activity	RNA Polymerase II Complex Binding Protein Binding Identical Protein Binding
	Biological Process	Cell Surface Receptor Signaling Pathway Regulation Of Autophagy Phosphorylation Negative Regulation Of Insulin Receptor Signaling Pathway Autophagosome-lysosome Fusion Negative Regulation Of 1-phosphatidylinositol-4-phosphate 5-kinase Activity 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate Biosynthetic Process Positive Regulation Of Autophagosome Assembly	Positive Regulation Of Cell Population Proliferation Regulation Of Cell Cycle Process MRNA 3'-end Processing Positive Regulation Of Transcription By RNA Polymerase II Dephosphorylation Of RNA Polymerase II C-terminal Domain
Pathways		Synthesis of PIPs at the plasma membrane PI5P Regulates TP53 Acetylation PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling Synthesis of PIPs in the nucleus	RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes
Drugs		Fostamatinib
Diseases
GWAS		Height ( 28552196 20881960 31562340)
Interacting Genes		17 interacting genes: BTK CDCA7L CLK1 CSNK2A1 HMBOX1 HSPB7 INO80B KYNU MLH1 PRPF3 PSMB1 RPRD1B TNFRSF1A TRIM55 TRIM63 UBQLN4 ZNF131	18 interacting genes: BIN3 CDCA8 DDIT4L HMG20A HOXC4 NUTF2 PFDN6 PIP4K2B PSMB1 RASSF3 SPG21 STEEP1 TERF2 TNPO2 TUBGCP4 UBE2I VAX1 VPS37C
Entrez ID		8396	58490
HPRD ID		04463	08513
Ensembl ID		ENSG00000276293	ENSG00000101413
Uniprot IDs		P78356	Q9NQG5
PDB IDs		1BO1 3WZZ 3X01 3X02 3X03 3X04 3X05 3X06 3X07 3X08 3X09 3X0A 3X0B 3X0C 6K4G 6K4H	4FLA 4FU3 4HFG 4NAD 4Q94 4Q96
Enriched GO Terms of Interacting Partners?
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