AMN and CDC42BPB

		AMN	CDC42BPB
Description		amnion associated transmembrane protein	CDC42 binding protein kinase beta
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GO Annotations	Cellular Component	Extracellular Space Plasma Membrane Clathrin-coated Pit Endosome Membrane Integral Component Of Membrane Apical Plasma Membrane Endocytic Vesicle Brush Border Membrane Protein-containing Complex Extracellular Exosome	Cytoplasm Cytosol Cytoskeleton Plasma Membrane Cell-cell Junction Lamellipodium Cell Leading Edge Actomyosin Extracellular Exosome
	Molecular Function	Signaling Receptor Binding Protein Binding	Magnesium Ion Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity ATP Binding Small GTPase Binding Protein-containing Complex Binding Protein Serine Kinase Activity
	Biological Process	Receptor-mediated Endocytosis Excretion Protein Localization Cobalamin Transport Golgi To Plasma Membrane Protein Transport	Protein Phosphorylation Cytoskeleton Organization Establishment Or Maintenance Of Cell Polarity Signal Transduction Cell Migration Peptidyl-threonine Phosphorylation Actomyosin Structure Organization Actin Cytoskeleton Reorganization Intracellular Signal Transduction
Pathways		Cobalamin (Cbl, vitamin B12) transport and metabolism Defective AMN causes hereditary megaloblastic anemia 1 Defective CUBN causes hereditary megaloblastic anemia 1 HDL clearance	CDC42 GTPase cycle RHOQ GTPase cycle RHOJ GTPase cycle
Drugs		Hydroxocobalamin
Diseases
GWAS		Body mass index ( 26426971)	Body mass index ( 26426971) Body shape index ( 34021172) Large B-cell lymphoma ( 21471979) Mean platelet volume ( 32888494) Refractive error ( 32231278) Serum alkaline phosphatase levels ( 33547301) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		4 interacting genes: CDC42BPB MTA1 STAMBP TECPR2	10 interacting genes: AMN CDC42 CDC42BPA KLC1 MAP2K5 MARK3 PPM1A PPP2CA PYGM RIPK1
Entrez ID		81693	9578
HPRD ID		09314	08516
Ensembl ID		ENSG00000166126	ENSG00000198752
Uniprot IDs		B3KP64 Q9BXJ7	A0A024R6N2 Q86XZ8 Q9Y5S2
PDB IDs		6GJE	3QFV 3TKU 4UAK 4UAL 5OTE 5OTF
Enriched GO Terms of Interacting Partners?
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