CDC42BPB and CDC42BPA

Number of citations of the paper that reports this interaction (PubMedID 23414517)
13

Data Source:
BioGRID (two hybrid)

		CDC42BPB	CDC42BPA
Description		CDC42 binding protein kinase beta	CDC42 binding protein kinase alpha
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoskeleton Plasma Membrane Cell-cell Junction Lamellipodium Cell Leading Edge Actomyosin Extracellular Exosome	Cytoplasm Cytosol Cytoskeleton Cell-cell Junction Lamellipodium Cell Leading Edge Actomyosin Extracellular Exosome
	Molecular Function	Magnesium Ion Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity ATP Binding Small GTPase Binding Protein-containing Complex Binding Protein Serine Kinase Activity	Magnesium Ion Binding Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Identical Protein Binding Protein Serine Kinase Activity
	Biological Process	Protein Phosphorylation Cytoskeleton Organization Establishment Or Maintenance Of Cell Polarity Signal Transduction Cell Migration Peptidyl-threonine Phosphorylation Actomyosin Structure Organization Actin Cytoskeleton Reorganization Intracellular Signal Transduction	Protein Phosphorylation Cell Migration Peptidyl-threonine Phosphorylation Actomyosin Structure Organization Actin Cytoskeleton Reorganization Intracellular Signal Transduction
Pathways		CDC42 GTPase cycle RHOQ GTPase cycle RHOJ GTPase cycle	CDC42 GTPase cycle RAC1 GTPase cycle RHOQ GTPase cycle RHOJ GTPase cycle
Drugs
Diseases
GWAS		Body mass index ( 26426971) Body shape index ( 34021172) Large B-cell lymphoma ( 21471979) Mean platelet volume ( 32888494) Refractive error ( 32231278) Serum alkaline phosphatase levels ( 33547301) Waist circumference adjusted for body mass index ( 34021172)	Blond vs. brown/black hair color ( 30531825) Blood urea nitrogen levels ( 31152163) Cardiovascular death or myocardial infarction in response to clopidogrel treatment ( 32472697) Diastolic blood pressure ( 28135244) Low density lipoprotein cholesterol levels ( 33339817) Macular thickness ( 30535121) Mercury levels ( 26025379) Myeloid white cell count ( 27863252) Neutrophil count ( 32888494) Optic cup area ( 25631615 31798171) Optic disc area ( 25631615 31798171 28073927) Optic disc size ( 31809533) SAPHO syndrome ( 33816493) Smoking initiation ( 33082346) Vertical cup-disc ratio (multi-trait analysis) ( 31959993) Waist circumference adjusted for body mass index ( 34021172) White blood cell count ( 32888494)
Interacting Genes		10 interacting genes: AMN CDC42 CDC42BPA KLC1 MAP2K5 MARK3 PPM1A PPP2CA PYGM RIPK1	10 interacting genes: CDC42 CDC42BPB LIMK1 LIMK2 MYL2 MYL9 PPM1A PPP1R12C SNAPIN TAF1
Entrez ID		9578	8476
HPRD ID		08516	04562
Ensembl ID		ENSG00000198752	ENSG00000143776
Uniprot IDs		A0A024R6N2 Q86XZ8 Q9Y5S2	Q5VT25
PDB IDs		3QFV 3TKU 4UAK 4UAL 5OTE 5OTF
Enriched GO Terms of Interacting Partners?
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