SETD7 and SIRT1

  • Number of citations of the paper that reports this interaction (PubMedID 21245319)
  • 52
  • Data Source:
  • BioGRID (affinity chromatography technology, affinity chromatography technology, pull down)

SETD7

SIRT1

Description SET domain containing 7, histone lysine methyltransferase sirtuin 1
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Diastolic blood pressure in combination therapy (beta blocker and thiazide diuretic) ( 29097388)
  • Ferritin levels ( 33491795)
  • Lean body mass ( 28552196)
  • Salty taste perception in obesity with metabolic syndrome ( 31005965)
  • Serum lycopene concentrations ( 26861389)
Interacting Genes 31 interacting genes: A1BG ATG16L1 DNMT1 E2F1 ESR1 H3-3A H3-4 H3C1 H3C14 H4C1 HCFC1 KLF4 L3MBTL1 MDM2 NR2F2 OGT PPP1R12A PRKAR1A RELA RIOK1 SERTAD1 SIL1 SIRT1 SMAD7 SOX2 STAT3 STEAP3 TAF10 TAF7 TP53 TRIM21 65 interacting genes: AFP AKT1 AR ARNTL BAZ1B BCL11A BHLHE41 BRIP1 CDK6 CENATAC CHFR CLOCK CSNK2B CTTN E2F1 EP300 ESRRA EZH2 FOS FOXM1 FOXO1 FOXO3 GAPDH H1-5 H3C1 HES1 HEY2 HIC1 HIPK2 HNF4A HOXB9 MAPK8 MPHOSPH8 MYCN NBN NDN NMNAT1 NR1H2 NR1H3 NR1H4 PARP1 PML PPARA PPARG PPARGC1A PRMT1 PSME3 RARA RELA RICTOR RRP8 SATB1 SETD7 SMAD7 SMURF2 SNW1 STK11 STK4 SUMO2 TP53 TP73 TRIM28 UBE2I USP22 VDR
Entrez ID 80854 23411
HPRD ID 16226 08381
Ensembl ID ENSG00000145391 ENSG00000096717
Uniprot IDs B5MCZ8 D6RJA0 Q8WTS6 A0A024QZQ1 A8K128 B0QZ35 E9PC49 Q96EB6
PDB IDs 1H3I 1MT6 1MUF 1N6A 1N6C 1O9S 1XQH 2F69 3CBM 3CBO 3CBP 3M53 3M54 3M55 3M56 3M57 3M58 3M59 3M5A 3OS5 3VUZ 3VV0 4E47 4J7F 4J7I 4J83 4J8O 4JDS 4JLG 5AYF 5EG2 5YLT 4I5I 4IF6 4IG9 4KXQ 4ZZH 4ZZI 4ZZJ 5BTR
Enriched GO Terms of Interacting Partners?
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