ADAM12 and SPRY4

  • Number of citations of the paper that reports this interaction (PubMedID 32296183)
  • 86
  • Data Source:
  • BioGRID (two hybrid)

ADAM12

SPRY4

Description ADAM metallopeptidase domain 12 sprouty RTK signaling antagonist 4
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Blood protein levels ( 30072576)
  • Endometrial cancer ( 24096698)
  • Extremely high intelligence ( 29731509)
  • Heel bone mineral density ( 30598549)
  • Intraocular pressure ( 30054594)
  • Itch intensity from mosquito bite ( 28199695)
  • Loneliness ( 27629369)
  • Metabolite levels (5-HIAA/ MHPG Ratio) ( 23319000)
  • Mild influenza (H1N1) infection ( 26379185)
  • Oppositional defiant disorder dimensions in attention-deficit hyperactivity disorder ( 26184070 27021288)
  • Placental abruption ( 29884306)
  • Schizophrenia, bipolar disorder or major depressive disorder x sex interaction ( 34099189)
  • Schizophrenia, bipolar disorder or recurrent major depressive disorder x sex interaction ( 34099189)
  • Thiazide-induced adverse metabolic effects in hypertensive patients ( 23400010)
  • Visceral fat ( 22589738)
Interacting Genes 42 interacting genes: ACTN2 ADAMTSL4 CYSRT1 DOCK1 EGF ESM1 FHL5 FSTL3 GRB2 GUCD1 HOXA1 IGFBP3 IGFBP5 KRT83 KRTAP1-1 KRTAP1-3 KRTAP10-8 KRTAP12-2 KRTAP3-1 KRTAP3-2 KRTAP4-12 KRTAP5-6 KRTAP5-9 KRTAP6-2 KRTAP9-2 KRTAP9-8 LCE5A MAPKBP1 NBPF19 NOTCH2NLA OTX1 PACSIN3 PIK3R1 RECK SH3D19 SLC15A2 SPRY1 SPRY4 SRC TFAP2D TUBGCP2 YES1 17 interacting genes: ADAM12 COL8A1 CREB5 EFEMP2 FHL2 HOXA1 KLHL38 KRTAP5-11 NUTF2 OTX1 POU4F2 RAF1 RIN3 TESK1 TNS2 VENTX ZDHHC17
Entrez ID 8038 81848
HPRD ID 04092 10466
Ensembl ID ENSG00000148848 ENSG00000187678
Uniprot IDs A8K6G4 O43184 U5NE98 A0A0C4DFS6 Q9C004
PDB IDs 3BUN
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?