TNIP3 and LITAF

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TNIP3	LITAF
Description		TNFAIP3 interacting protein 3	lipopolysaccharide induced TNF factor
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol	Golgi Membrane Nucleoplasm Lysosomal Membrane Golgi Apparatus Plasma Membrane Cytoplasmic Side Of Plasma Membrane Intracellular Membrane-bounded Organelle Cytoplasmic Side Of Early Endosome Membrane Cytoplasmic Side Of Late Endosome Membrane Cytoplasmic Side Of Lysosomal Membrane
	Molecular Function	Protein Binding Polyubiquitin Modification-dependent Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Zinc Ion Binding WW Domain Binding
	Biological Process	MyD88-independent Toll-like Receptor Signaling Pathway Regulation Of Transcription By RNA Polymerase II Inflammatory Response Toll-like Receptor 4 Signaling Pathway Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling Cellular Response To Lipopolysaccharide	Regulation Of Cytokine Production Regulation Of Transcription By RNA Polymerase II Aging Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Transcription By RNA Polymerase II Cellular Response To Lipopolysaccharide Negative Regulation Of NIK/NF-kappaB Signaling
Pathways		Ovarian tumor domain proteases
Drugs
Diseases
GWAS		Breast cancer ( 23468962) Multiple sclerosis ( 31604244)	Allergic disease (asthma, hay fever or eczema) ( 29083406) Colorectal or endometrial cancer ( 26621817) Crohn's disease ( 28067908) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Electrocardiographic traits (multivariate) ( 32602732) Gallstone disease ( 30504769) Heel bone mineral density ( 30598549) Hip index ( 34021172) Inflammatory bowel disease ( 28067908 23128233) LDL cholesterol levels ( 32203549) Liver enzyme levels (gamma-glutamyl transferase) ( 33972514) Low density lipoprotein cholesterol levels ( 32154731 33339817) Monocyte percentage of white cells ( 32888494) QT interval ( 23166209 30679814 29213071 24952745 19305408 19305409 29874175) Response to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 3 peripheral neuropathy) ( 24554482) TPE interval (resting) ( 32386560) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		26 interacting genes: BBS12 CCN3 CYSRT1 DAZAP2 FAM161A KPNA3 KRT40 KRTAP10-3 KRTAP10-8 LITAF LZTS2 MAGEA2 MAGEA2B MTUS2 NBPF19 NOTCH2NLA NTAQ1 PIBF1 PLSCR3 TAX1BP1 TCEANC TNIP1 TRIM55 TRIM63 UBC ZBTB8A	43 interacting genes: ARID5A ATXN1 BAG3 CALCOCO2 COMT CREB5 DAZAP2 EPN1 EPN2 EPN3 GGA3 HGS HIP1 HPCAL1 HPCAL4 ITCH KCNIP1 KCNIP4 N4BP1 NCALD NEDD4 OPTN PLOD2 POGZ RADIL RASSF3 REEP6 RNF208 RPS27A SMAD2 STAM2 STAT6 TAX1BP1 TNIP1 TNIP3 TOM1 UBA52 UBQLN1 UBQLN2 VENTX VSNL1 WWOX ZIC1
Entrez ID		79931	9516
HPRD ID		16268	10354
Ensembl ID		ENSG00000050730	ENSG00000189067
Uniprot IDs		Q96KP6	Q99732
PDB IDs
Enriched GO Terms of Interacting Partners?
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