PRR5L and PHAF1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		PRR5L	PHAF1
Description		proline rich 5 like	phagosome assembly factor 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	TORC2 Complex	Phagophore Assembly Site Trans-Golgi Network Dendrite Synaptic Vesicle Membrane
	Molecular Function	Protein Binding Ubiquitin Protein Ligase Binding	Protein Binding
	Biological Process	Negative Regulation Of Protein Phosphorylation Positive Regulation Of Protein Phosphorylation Negative Regulation Of Signal Transduction Regulation Of Fibroblast Migration Positive Regulation Of Phosphatidylinositol 3-kinase Signaling Cellular Response To Oxidative Stress TORC2 Signaling Positive Regulation Of MRNA Catabolic Process Positive Regulation Of Intracellular Protein Transport	Golgi To Plasma Membrane Protein Transport
Pathways
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29679657) Asthma ( 31361310 30929738 32296059 31619474) Asthma (childhood onset) ( 30929738) Atopic dermatitis ( 26482879 23727859) Body shape index ( 34021172) Hip index ( 34021172) Idiopathic inflammatory myopathy ( 26362759) Inflammatory skin disease ( 25574825) Juvenile idiopathic arthritis (oligoarticular or rheumatoid factor-negative polyarticular) ( 23603761) Mean corpuscular volume ( 32888494) Multiple sclerosis ( 31604244 24076602) Photic sneeze reflex ( 27182965) Red blood cell count ( 32888494) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		15 interacting genes: CCDC91 EFHC1 FHL2 FHL3 HSF2BP KANK2 MAD2L2 MISP MLH1 MORN3 MTOR PHAF1 SCNM1 USP2 ZMYND12	13 interacting genes: APP ATXN3 CBFA2T2 CCDC102B CYB5B ESRP2 KIF17 MPPED1 NPBWR2 PRR5L QSOX1 TOLLIP TSHZ2
Entrez ID		79899	80262
HPRD ID		07854	17460
Ensembl ID		ENSG00000135362	ENSG00000125149
Uniprot IDs		B3KNU3 Q6MZQ0	A0A024R6W4 Q9BSU1
PDB IDs
Enriched GO Terms of Interacting Partners?
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