PHAF1 and ATXN3

  • Number of citations of the paper that reports this interaction (PubMedID 16713569)
  • 337
  • Data Source:
  • BioGRID (two hybrid, affinity chromatography technology)
  • HPRD (two hybrid)

PHAF1

ATXN3

Description phagosome assembly factor 1 ataxin 3
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Amyotrophic lateral sclerosis ( 29566793)
  • Coronary artery calcification ( 23870195)
  • HDL cholesterol levels x thiazide or thiazide-like diuretics use interaction ( 31806883)
  • Height ( 18391950 18391951)
  • Hip circumference adjusted for BMI ( 34021172)
  • LDL cholesterol levels x loop diuretics use interaction ( 31806883)
  • Orofacial clefts ( 22419666)
  • Refractive error ( 32231278)
  • Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes 13 interacting genes: APP ATXN3 CBFA2T2 CCDC102B CYB5B ESRP2 KIF17 MPPED1 NPBWR2 PRR5L QSOX1 TOLLIP TSHZ2 56 interacting genes: ANXA7 APP ARHGAP19 ARHGDIA ASIC1 CAPN1 CAPN2 CASP1 CDKN1A CHEK1 CSNK2B DNM2 EWSR1 GABARAP GSK3B HDAC6 KAT2B KPNA2 MAP1LC3A MAP1LC3C MAP3K1 MKNK1 NCOR1 NEDD8 PHAF1 PICK1 PJA1 PRKN PSMD7 RAD23A RAD23B RFFL RPS6KA1 SMURF1 SQSTM1 STUB1 SUMO1 TEX11 TK1 TP53 TRAF6 TRIM54 TRIM55 TRIM63 TUBA1A TUBB UBB UBC UBE2D3 UBE2L3 UBE2S UBE2W UBE4B UBQLN1 USP21 VCP
Entrez ID 80262 4287
HPRD ID 17460 06131
Ensembl ID ENSG00000125149 ENSG00000066427
Uniprot IDs A0A024R6W4 Q9BSU1 A0A0A0MS38 C9JQV6 P54252
PDB IDs 1YZB 2AGA 2DOS 2JRI 2KLZ 4WTH 4YS9
Enriched GO Terms of Interacting Partners?
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