EFHC2 and ESRRG

  • Number of citations of the paper that reports this interaction (PubMedID 32296183)
  • 86
  • Data Source:
  • BioGRID (two hybrid)

EFHC2

ESRRG

Description EF-hand domain containing 2 estrogen related receptor gamma
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Body mass index and diastolic blood pressure (bivariate analysis) ( 33539483)
  • Glaucoma (primary open-angle) ( 33627673)
  • Mean arterial pressure ( 29403010)
  • Adventurousness ( 30643258)
  • Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs) ( 23648065)
  • Adverse response to drug ( 30420678)
  • Alcohol consumption ( 23743675)
  • Breast cancer ( 29059683)
  • Cardiac hypertrophy ( 21348951)
  • Cleft lip with or without cleft palate (maternal periconceptional vitamin use interaction) ( 29535761)
  • Depressive symptom (anhedonia) (ordinal trait) ( 31530331)
  • Dialysis-related mortality ( 21546767)
  • Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)
  • Energy expenditure (24h) ( 28476931)
  • General cognitive ability ( 29844566)
  • General risk tolerance (MTAG) ( 30643258)
  • Gut microbiota relative abundance (Ruminococcus belonging to family Erysipelotrichaceae) ( 33208821)
  • Hematocrit ( 32888494)
  • Hemoglobin ( 32888494)
  • Intelligence (MTAG) ( 29326435)
  • Intracranial aneurysm ( 29531279)
  • LDL cholesterol levels in HIV infection ( 33109212)
  • Major depressive disorder ( 23377640)
  • Mean arterial pressure (alcohol consumption interaction) ( 24376456)
  • Nicotine dependence and major depression (severity of comorbidity) ( 30287806)
  • Optic nerve measurement (cup area) ( 20395239)
  • Photic sneeze reflex ( 27182965)
  • Post bronchodilator FEV1 ( 26634245)
  • Post bronchodilator FEV1/FVC ratio ( 26634245)
  • Refractive error ( 32231278)
  • Sleep duration ( 25469926)
  • Smoking status (ever vs never smokers) ( 30643258)
  • Tea consumption ( 31046077)
  • Weight ( 28552196)
Interacting Genes 100 interacting genes: - AASDHPPT ARHGEF5 ARMC7 CABP2 CACNB4 CARD9 CCDC102B CCDC120 CCDC13 CCDC57 CCHCR1 CCNG2 CDKN2A CLIC3 COPE CPNE2 CPNE7 CYFIP1 DCLK1 DDX6 DGCR6 DRC7 EDC3 EFHC1 EGLN3 EMD ENKD1 ESRRG EXOC8 EXOSC5 FAM107A FAM124B FAM214B FAM221B FBXL19 GEM GLYCTK GOLGA1 GPKOW GRB2 GYS1 HDAC4 HGS HNRNPLL INPP5J JAKMIP2 KANK2 KCTD7 KIF9 L3MBTL2 LMNB2 LMO2 LNX1 LONRF1 MAGOHB MAPK9 MID2 MISP MYLIP MYO5B NCDN NCK2 NDOR1 NEK6 NFKBID NME7 NR3C1 PBLD PHF1 PIBF1 PICK1 PLOD3 POLR1C PRPF18 PTK6 QARS1 RAD51D RCOR3 RECK RHOBTB3 RUNX1T1 SNRNP25 SOGA1 SPATA18 SPG21 STK16 TBC1D1 TBC1D22B TEKT4 TRIM42 TRIM50 TSSK3 TUBGCP4 TXK U2AF1 USP2 ZBTB16 ZFHX3 ZZZ3 59 interacting genes: ADCY4 APP ARHGEF15 ATM BPHL C22orf23 CALM1 CAMK2G CCDC33 DAXX DEUP1 DUT EBP EFHC2 ESRRA ESRRB EXOSC7 FAM107A FAM9A FASTK HGS HIF1A KIFC3 LRRK2 MARK1 MCC MEOX2 MFHAS1 MRM1 NCOA1 NR0B1 NR0B2 NRIP1 NUP160 PAX6 PNRC1 PNRC2 POMC PPARGC1A PPARGC1B PROX1 PSMC5 RBIS REL RINT1 SHTN1 SNIP1 SP1 SRA1 SRPK1 SUMO1P1 TLE1 TNNI1 TNNI2 TRERF1 TULP3 UBL7 VAX1 ZNF438
Entrez ID 80258 2104
HPRD ID 06540 04274
Ensembl ID ENSG00000183690 ENSG00000196482
Uniprot IDs Q5JST6 B7Z5E9 C0SQ93 F1D8R5 F1D8R6 P62508
PDB IDs 2Z13 2Z14 1KV6 1TFC 1VJB 2E2R 2EWP 2GP7 2GPO 2GPP 2GPU 2GPV 2P7A 2P7G 2P7Z 2ZAS 2ZBS 2ZKC 5YSO 6A6K 6I61 6I62 6I63 6I64 6I65 6I66 6I67 6K3N 6KNR
Enriched GO Terms of Interacting Partners?
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