HMBOX1 and TUFM

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		HMBOX1	TUFM
Description		homeobox containing 1	Tu translation elongation factor, mitochondrial
Image
GO Annotations	Cellular Component	Chromosome, Telomeric Region Chromatin Nucleus Nucleoplasm Cytoplasm Centrosome Cytosol Cajal Body Nuclear Body PML Body	Mitochondrion Membrane Mitochondrial Nucleoid Synapse Extracellular Exosome
	Molecular Function	Double-stranded Telomeric DNA Binding Protein Binding Telomeric DNA Binding Identical Protein Binding Sequence-specific DNA Binding Protein-containing Complex Binding Sequence-specific Double-stranded DNA Binding	RNA Binding Translation Elongation Factor Activity GTPase Activity Protein Binding GTP Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Telomere Maintenance Via Telomerase Positive Regulation Of Chromatin Binding Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Regulation Of Telomerase Activity Positive Regulation Of Telomerase Activity	Translational Elongation Response To Ethanol Mitochondrial Translational Elongation
Pathways			Mitochondrial translation elongation
Drugs			Zinc Guanosine-5'-Diphosphate Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS		Obesity-related traits ( 23251661)	Alcohol consumption (drinks per week) ( 30643258) Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Body fat percentage ( 26833246) Body mass index ( 20935630) Brain morphology (MOSTest) ( 32665545) Crohn's disease ( 28067908) Educational attainment ( 25201988) Estimated glomerular filtration rate ( 31152163) Extremely high intelligence ( 29520040) Hip circumference adjusted for BMI ( 25673412) Inflammatory bowel disease ( 28067908) Intelligence ( 28530673) Lamb consumption ( 32066663) Walking pace ( 33128006)
Interacting Genes		100 interacting genes: ABITRAM AEBP2 ANKRD36 APP ASB7 ATP5PO BAZ2B BEND7 BRD1 BYSL C8orf33 CARD9 CBX8 CCDC187 CCNG1 CDC7 CDCA8 CDK18 DAB1 DNTTIP1 DYNLL1 DYNLL2 ENKD1 ENTPD2 FAM13C FAM161A FAM217B FAM74A4 FAM90A1 FARS2 FGF11 FNDC11 FRMD6 FXR2 GAS2L2 GNL3L GSC2 INO80B IPO13 KAT5 KIF9 LMO1 LMO3 LNX1 MAGEH1 MCRS1 MEOX1 MEOX2 MFAP1 MORF4L1 MORF4L2 MRPL11 MRPL28 PAX5 PAX6 PIAS2 PICK1 PIP4K2B PKD1P1 POLDIP3 POLL PRKAA1 PRKAA2 PRPF18 RBMY2FP RCOR3 REEP6 RPL9 RPS25 SAP30L SCNM1 SDCBP SFR1 SH2D4A SNRPB2 SNW1 SYT6 TBP TCEA2 TCEANC TSGA10IP TUFM U2AF2 UBA6 UBE2I UBE2Z VAX1 VPS72 WT1 ZBTB24 ZBTB26 ZFYVE26 ZMAT2 ZMYM5 ZNF250 ZNF337 ZNF417 ZNF581 ZNF587 ZNF688	23 interacting genes: ARL6IP1 ASPH ATP6V1A CMTM5 DGAT2L6 DOC2A EXOSC6 FAM9B FUNDC1 HMBOX1 LINC01554 MTIF3 MYH9 OGT PCAT1 PDGFRB PPP1R16B PTEN RHBDD2 SYP TAOK2 TNFRSF10D ZDHHC15
Entrez ID		79618	7284
HPRD ID		07964	03861
Ensembl ID		ENSG00000147421	ENSG00000178952
Uniprot IDs		D3DSU2 Q6NT76	A0A384ME17 P49411
PDB IDs		2CUF 4J19	7A5G
Enriched GO Terms of Interacting Partners?
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