TUFM and ZDHHC15

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TUFM	ZDHHC15
Description		Tu translation elongation factor, mitochondrial	zinc finger DHHC-type palmitoyltransferase 15
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Membrane Mitochondrial Nucleoid Synapse Extracellular Exosome	Golgi Membrane Endoplasmic Reticulum Golgi Apparatus Postsynaptic Density Integral Component Of Golgi Membrane Postsynapse
	Molecular Function	RNA Binding Translation Elongation Factor Activity GTPase Activity Protein Binding GTP Binding	Protein Binding Zinc Ion Binding Palmitoyltransferase Activity Protein-cysteine S-myristoyltransferase Activity Protein-cysteine S-palmitoyltransferase Activity Protein-cysteine S-stearoyltransferase Activity
	Biological Process	Translational Elongation Response To Ethanol Mitochondrial Translational Elongation	Protein Targeting To Membrane Synaptic Vesicle Maturation Peptidyl-L-cysteine S-palmitoylation Protein Palmitoylation Regulation Of Dendritic Spine Morphogenesis Protein Localization To Postsynapse Protein Localization To Membrane Protein Targeting To Golgi Apparatus Positive Regulation Of Dendrite Development
Pathways		Mitochondrial translation elongation
Drugs		Zinc Guanosine-5'-Diphosphate Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS		Alcohol consumption (drinks per week) ( 30643258) Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Body fat percentage ( 26833246) Body mass index ( 20935630) Brain morphology (MOSTest) ( 32665545) Crohn's disease ( 28067908) Educational attainment ( 25201988) Estimated glomerular filtration rate ( 31152163) Extremely high intelligence ( 29520040) Hip circumference adjusted for BMI ( 25673412) Inflammatory bowel disease ( 28067908) Intelligence ( 28530673) Lamb consumption ( 32066663) Walking pace ( 33128006)
Interacting Genes		23 interacting genes: ARL6IP1 ASPH ATP6V1A CMTM5 DGAT2L6 DOC2A EXOSC6 FAM9B FUNDC1 HMBOX1 LINC01554 MTIF3 MYH9 OGT PCAT1 PDGFRB PPP1R16B PTEN RHBDD2 SYP TAOK2 TNFRSF10D ZDHHC15	48 interacting genes: ADCYAP1R1 ARL13B BNIP3 C14orf180 CD79A CELA2B CERCAM CLEC10A CLRN1 CREB3L1 CYB5R3 DHRSX ERGIC3 FAM241B GIMAP1 GOLGA7B GPR152 LEMD1 LEPROTL1 LHFPL5 LMNA LSMEM1 MCEMP1 MTIF3 ORMDL1 ORMDL2 PEX16 PLLP PRAF2 PVR RUSF1 SLC10A6 SMIM1 SNORC STX3 TBXA2R TMEFF2 TMEM120B TMEM128 TMEM14C TMEM222 TMEM42 TMEM52B TNFRSF10B TSNARE1 TUFM VAPB YIPF4
Entrez ID		7284	158866
HPRD ID		03861	06758
Ensembl ID		ENSG00000178952	ENSG00000102383
Uniprot IDs		A0A384ME17 P49411	B3KY34 Q96MV8
PDB IDs		7A5G
Enriched GO Terms of Interacting Partners?
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