TUFM and TAOK2

		TUFM	TAOK2
Description		Tu translation elongation factor, mitochondrial	TAO kinase 2
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Membrane Mitochondrial Nucleoid Synapse Extracellular Exosome	Nucleoplasm Nucleolus Cytoplasm Cytosol Actin Cytoskeleton Integral Component Of Membrane Axon Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle Neuron Projection Receptor Complex Dendritic Growth Cone Axonal Growth Cone
	Molecular Function	RNA Binding Translation Elongation Factor Activity GTPase Activity Protein Binding GTP Binding	Protein Serine/threonine Kinase Activity MAP Kinase Kinase Kinase Activity Protein Binding ATP Binding Mitogen-activated Protein Kinase Kinase Binding Neuropilin Binding Tau Protein Binding Tau-protein Kinase Activity Protein Serine Kinase Activity
	Biological Process	Translational Elongation Response To Ethanol Mitochondrial Translational Elongation	MAPK Cascade Regulation Of Cell Growth Protein Phosphorylation Protein Targeting To Membrane Apoptotic Process Cellular Response To DNA Damage Stimulus Mitotic G2 DNA Damage Checkpoint Signaling Axonogenesis Regulation Of Cell Shape Cell Migration Actin Cytoskeleton Organization Positive Regulation Of Protein Autophosphorylation Activation Of Protein Kinase Activity Positive Regulation Of Stress-activated MAPK Cascade Regulation Of Actin Cytoskeleton Organization Intracellular Signal Transduction Regulation Of MAPK Cascade Positive Regulation Of MAPK Cascade Positive Regulation Of JNK Cascade Protein Autophosphorylation Focal Adhesion Assembly Neuron Projection Morphogenesis Stress-activated MAPK Cascade Basal Dendrite Morphogenesis Basal Dendrite Arborization
Pathways		Mitochondrial translation elongation
Drugs		Zinc Guanosine-5'-Diphosphate Zinc acetate Zinc chloride Zinc sulfate, unspecified form	Dexfosfoserine Fostamatinib
Diseases
GWAS		Alcohol consumption (drinks per week) ( 30643258) Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Body fat percentage ( 26833246) Body mass index ( 20935630) Brain morphology (MOSTest) ( 32665545) Crohn's disease ( 28067908) Educational attainment ( 25201988) Estimated glomerular filtration rate ( 31152163) Extremely high intelligence ( 29520040) Hip circumference adjusted for BMI ( 25673412) Inflammatory bowel disease ( 28067908) Intelligence ( 28530673) Lamb consumption ( 32066663) Walking pace ( 33128006)	Adult body size ( 32376654) Apolipoprotein A1 levels ( 32203549) Autism spectrum disorder or schizophrenia ( 28540026) Body fat distribution (arm fat ratio) ( 30664634) Body mass index ( 29273807) Brain morphology (MOSTest) ( 32665545) Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) HDL cholesterol levels ( 32203549) High density lipoprotein cholesterol levels ( 31928498) Metabolic syndrome ( 31589552) Schizophrenia ( 28991256 25056061 29483656 30285260) Triglyceride levels ( 32203549 32154731) Waist circumference ( 31928498)
Interacting Genes		23 interacting genes: ARL6IP1 ASPH ATP6V1A CMTM5 DGAT2L6 DOC2A EXOSC6 FAM9B FUNDC1 HMBOX1 LINC01554 MTIF3 MYH9 OGT PCAT1 PDGFRB PPP1R16B PTEN RHBDD2 SYP TAOK2 TNFRSF10D ZDHHC15	22 interacting genes: BCKDK CIDEB DOC2A EIF3C ELK1 KLHL12 KRTAP6-3 MAP2K3 MAP2K6 MEGF10 RCHY1 RTRAF SETD1A TLE3 TUBA1A TUBA4A TUBB TUFM USF1 ZNF267 ZNF597 ZNF646
Entrez ID		7284	9344
HPRD ID		03861	18147
Ensembl ID		ENSG00000178952	ENSG00000149930
Uniprot IDs		A0A384ME17 P49411	Q9UL54
PDB IDs		7A5G
Enriched GO Terms of Interacting Partners?
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