TRAPPC6A and GINS3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TRAPPC6A	GINS3
Description		trafficking protein particle complex subunit 6A	GINS complex subunit 3
Image
GO Annotations	Cellular Component	Endoplasmic Reticulum Cis-Golgi Network Trans-Golgi Network Cytosol TRAPP Complex	GINS Complex Nucleoplasm CMG Complex
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Regulation Of GTPase Activity Melanosome Assembly	Mitotic DNA Replication Initiation
Pathways		COPII-mediated vesicle transport RAB GEFs exchange GTP for GDP on RABs	Unwinding of DNA Unwinding of DNA
Drugs		S-palmitoyl-L-cysteine
Diseases
GWAS		Alanine aminotransferase levels ( 33339817) Alzheimer's disease (onset between ages 58 and 79) ( 30979435) Alzheimer's disease or HDL levels (pleiotropy) ( 30805717) Aspartate aminotransferase levels ( 33339817) Cerebrospinal fluid AB1-42 levels ( 28247064)	Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Electrocardiographic traits (multivariate) ( 32602732) QT interval ( 19305408) TPE interval (resting) ( 32386560)
Interacting Genes		47 interacting genes: BAG4 CAVIN2 CD2BP2 CRYAB CTDSP1 EFS EYA2 FOXN1 GGA3 GINS3 GOLGA6A GORASP2 HOXA1 HSPB8 IKZF3 INCA1 KANK4 KRTAP13-2 LHX4 MYOZ3 PAX6 PFDN5 PRR22 RAB3IP RAD54B REL RUSC1 SCOC SERTAD3 SF3B5 SMUG1 TAX1BP1 TEPSIN TRAPPC10 TRAPPC12 TRAPPC2 TRAPPC2L TRAPPC3 TRAPPC3L TRAPPC6B TRIM35 TTC23 UBAP2 YPEL3 ZFP90 ZMIZ2 ZNRD2	9 interacting genes: CTNNA3 GINS4 KRT80 MEOX2 MYO15B SETD6 SMARCD1 TRAPPC6A VAC14
Entrez ID		79090	64785
HPRD ID		14503	07842
Ensembl ID		ENSG00000007255	ENSG00000181938
Uniprot IDs		B7TZ90 O75865	A0A0S2Z5L0 A0A0S2Z5L4 A0A0S2Z5P2 Q9BRX5
PDB IDs		2C0J 2J3T	2E9X 2EHO 2Q9Q 6XTX 6XTY
Enriched GO Terms of Interacting Partners?
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