TRAPPC6A and TRAPPC12

Number of citations of the paper that reports this interaction (PubMedID 26186194)
524

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, two hybrid, two hybrid)

		TRAPPC6A	TRAPPC12
Description		trafficking protein particle complex subunit 6A	trafficking protein particle complex subunit 12
Image			No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Cis-Golgi Network Trans-Golgi Network Cytosol TRAPP Complex	Kinetochore Nucleus Nucleoplasm Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Cytosol TRAPP Complex Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Regulation Of GTPase Activity Melanosome Assembly	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Golgi Organization Metaphase Plate Congression Regulation Of Kinetochore Assembly Positive Regulation Of Protein Localization To Kinetochore
Pathways		COPII-mediated vesicle transport RAB GEFs exchange GTP for GDP on RABs	RAB GEFs exchange GTP for GDP on RABs
Drugs		S-palmitoyl-L-cysteine
Diseases
GWAS		Alanine aminotransferase levels ( 33339817) Alzheimer's disease (onset between ages 58 and 79) ( 30979435) Alzheimer's disease or HDL levels (pleiotropy) ( 30805717) Aspartate aminotransferase levels ( 33339817) Cerebrospinal fluid AB1-42 levels ( 28247064)	Neuritic plaques or neurofibrillary tangles or cerebral amyloid angiopathy (pleiotropy) ( 29458411) Serum immune biomarker levels ( 32066700)
Interacting Genes		47 interacting genes: BAG4 CAVIN2 CD2BP2 CRYAB CTDSP1 EFS EYA2 FOXN1 GGA3 GINS3 GOLGA6A GORASP2 HOXA1 HSPB8 IKZF3 INCA1 KANK4 KRTAP13-2 LHX4 MYOZ3 PAX6 PFDN5 PRR22 RAB3IP RAD54B REL RUSC1 SCOC SERTAD3 SF3B5 SMUG1 TAX1BP1 TEPSIN TRAPPC10 TRAPPC12 TRAPPC2 TRAPPC2L TRAPPC3 TRAPPC3L TRAPPC6B TRIM35 TTC23 UBAP2 YPEL3 ZFP90 ZMIZ2 ZNRD2	13 interacting genes: ARNTL FBXO7 HNRNPA2B1 LIN7B MTDH RSKR TFCP2 TRAPPC10 TRAPPC3L TRAPPC4 TRAPPC6A TRAPPC6B TRAPPC9
Entrez ID		79090	51112
HPRD ID		14503	15580
Ensembl ID		ENSG00000007255	ENSG00000171853
Uniprot IDs		B7TZ90 O75865	A0A0J9YXQ9 Q8WVT3
PDB IDs		2C0J 2J3T
Enriched GO Terms of Interacting Partners?
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