TRAPPC6A and CD2BP2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TRAPPC6A	CD2BP2
Description		trafficking protein particle complex subunit 6A	CD2 cytoplasmic tail binding protein 2
Image
GO Annotations	Cellular Component	Endoplasmic Reticulum Cis-Golgi Network Trans-Golgi Network Cytosol TRAPP Complex	Fibrillar Center Nucleus Nucleoplasm U5 SnRNP Cytoplasm Cytosol Nuclear Speck U4/U6 X U5 Tri-snRNP Complex
	Molecular Function	Protein Binding	Protein Binding Ribonucleoprotein Complex Binding
	Biological Process	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Regulation Of GTPase Activity Melanosome Assembly	Spliceosomal Tri-snRNP Complex Assembly
Pathways		COPII-mediated vesicle transport RAB GEFs exchange GTP for GDP on RABs	mRNA Splicing - Major Pathway
Drugs		S-palmitoyl-L-cysteine
Diseases
GWAS		Alanine aminotransferase levels ( 33339817) Alzheimer's disease (onset between ages 58 and 79) ( 30979435) Alzheimer's disease or HDL levels (pleiotropy) ( 30805717) Aspartate aminotransferase levels ( 33339817) Cerebrospinal fluid AB1-42 levels ( 28247064)	Brain morphology (MOSTest) ( 32665545)
Interacting Genes		47 interacting genes: BAG4 CAVIN2 CD2BP2 CRYAB CTDSP1 EFS EYA2 FOXN1 GGA3 GINS3 GOLGA6A GORASP2 HOXA1 HSPB8 IKZF3 INCA1 KANK4 KRTAP13-2 LHX4 MYOZ3 PAX6 PFDN5 PRR22 RAB3IP RAD54B REL RUSC1 SCOC SERTAD3 SF3B5 SMUG1 TAX1BP1 TEPSIN TRAPPC10 TRAPPC12 TRAPPC2 TRAPPC2L TRAPPC3 TRAPPC3L TRAPPC6B TRIM35 TTC23 UBAP2 YPEL3 ZFP90 ZMIZ2 ZNRD2	15 interacting genes: ACAD11 AKNA CD2 CHRM3 CSNK2A1 LRRK1 OGT PRPF6 PSMF1 SMU1 SNRPB TRAPPC6A TXNL4A WBP11 ZNHIT2
Entrez ID		79090	10421
HPRD ID		14503	05127
Ensembl ID		ENSG00000007255	ENSG00000169217
Uniprot IDs		B7TZ90 O75865	A0A024QZC1 O95400
PDB IDs		2C0J 2J3T	1GYF 1L2Z 1SYX 4BWS
Enriched GO Terms of Interacting Partners?
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