ZMYM2 and PAICS

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		ZMYM2	PAICS
Description		zinc finger MYM-type containing 2	phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol PML Body	Cytoplasm Cytosol Membrane Extracellular Exosome
	Molecular Function	Protein Binding Zinc Ion Binding Ubiquitin Conjugating Enzyme Binding	Phosphoribosylaminoimidazole Carboxylase Activity Phosphoribosylaminoimidazolesuccinocarboxamide Synthase Activity Protein Binding ATP Binding Identical Protein Binding 5-amino-4-imidazole Carboxylate Lyase Activity Cadherin Binding
	Biological Process	Biological_process	'de Novo' IMP Biosynthetic Process Purine Nucleobase Biosynthetic Process
Pathways		Signaling by cytosolic FGFR1 fusion mutants Signaling by FGFR1 in disease Signaling by FLT3 fusion proteins Signaling by FLT3 fusion proteins	Purine ribonucleoside monophosphate biosynthesis
Drugs			Aspartic acid
Diseases
GWAS		Adult body size ( 32376654) Facial emotion recognition (happy faces) ( 28608620) Hand grip strength ( 29691431)
Interacting Genes		26 interacting genes: CEBPE CREB1 CREBBP FBXL17 FUS GMCL1 HNRNPA2B1 HNRNPH3 IKZF3 PAICS PTBP1 RCOR1 SFPQ SKIL SMAD3 SMAD4 SNIP1 SREBF2 SUMO1 SUMO2 TSC22D2 UBE2A UBE2I UBTF ZBTB3 ZNF512B	21 interacting genes: CDC37 CEP76 CHD3 FXR1 FXR2 L3MBTL2 LNX1 MOB4 NIF3L1 NUDT18 PIAS2 PILRA PRKAG1 PTPRC RAD54L2 RNF4 SMARCD1 TERF1 UBE2I UBE3A ZMYM2
Entrez ID		7750	10606
HPRD ID		03745	01401
Ensembl ID		ENSG00000121741	ENSG00000128050
Uniprot IDs		A0A024RDS3 A8K126 Q9UBW7	P22234
PDB IDs			2H31 6YB8 6YB9
Enriched GO Terms of Interacting Partners?
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