PAICS and RAD54L2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		PAICS	RAD54L2
Description		phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase	RAD54 like 2
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Membrane Extracellular Exosome	Nucleus
	Molecular Function	Phosphoribosylaminoimidazole Carboxylase Activity Phosphoribosylaminoimidazolesuccinocarboxamide Synthase Activity Protein Binding ATP Binding Identical Protein Binding 5-amino-4-imidazole Carboxylate Lyase Activity Cadherin Binding	DNA Binding DNA Helicase Activity Protein Binding ATP Binding ATP Hydrolysis Activity ATP-dependent Chromatin Remodeler Activity
	Biological Process	'de Novo' IMP Biosynthetic Process Purine Nucleobase Biosynthetic Process	DNA Duplex Unwinding
Pathways		Purine ribonucleoside monophosphate biosynthesis
Drugs		Aspartic acid
Diseases
GWAS			Estimated glomerular filtration rate ( 31152163)
Interacting Genes		21 interacting genes: CDC37 CEP76 CHD3 FXR1 FXR2 L3MBTL2 LNX1 MOB4 NIF3L1 NUDT18 PIAS2 PILRA PRKAG1 PTPRC RAD54L2 RNF4 SMARCD1 TERF1 UBE2I UBE3A ZMYM2	42 interacting genes: AR ATN1 ATXN1 ATXN1L BANP BHLHE40 CBX3 FAM118B FXR2 HMG20A HNRNPCL1 HOMER1 IMPDH1 IMPDH2 KIFC3 KRTAP6-3 LCE1D LCE1F NR3C1 NR5A1 NR5A2 PAICS PIAS1 POU1F1 PPARG PSMA3 RBPMS RUNX1T1 RXRA SIAH1 SQSTM1 SUMO1 SUMO2 TAX1BP1 TFAP2D THAP1 TRAF2 TRAF4 UBE2I VCX ZBTB26 ZC2HC1A
Entrez ID		10606	23132
HPRD ID		01401	10018
Ensembl ID		ENSG00000128050	ENSG00000164080
Uniprot IDs		P22234	B3KV54 Q9Y4B4
PDB IDs		2H31 6YB8 6YB9
Enriched GO Terms of Interacting Partners?
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