PAICS and PILRA

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		PAICS	PILRA
Description		phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase	paired immunoglobin like type 2 receptor alpha
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GO Annotations	Cellular Component	Cytoplasm Cytosol Membrane Extracellular Exosome	Plasma Membrane Integral Component Of Membrane Extracellular Exosome
	Molecular Function	Phosphoribosylaminoimidazole Carboxylase Activity Phosphoribosylaminoimidazolesuccinocarboxamide Synthase Activity Protein Binding ATP Binding Identical Protein Binding 5-amino-4-imidazole Carboxylate Lyase Activity Cadherin Binding	Protein Binding MHC Class I Protein Binding
	Biological Process	'de Novo' IMP Biosynthetic Process Purine Nucleobase Biosynthetic Process	Signal Transduction
Pathways		Purine ribonucleoside monophosphate biosynthesis	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Drugs		Aspartic acid
Diseases
GWAS			Advanced age-related macular degeneration ( 26691988) Blood protein levels ( 30072576) Brain morphology (MOSTest) ( 32665545) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Red cell distribution width ( 32888494) Refractive error ( 32231278) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		21 interacting genes: CDC37 CEP76 CHD3 FXR1 FXR2 L3MBTL2 LNX1 MOB4 NIF3L1 NUDT18 PIAS2 PILRA PRKAG1 PTPRC RAD54L2 RNF4 SMARCD1 TERF1 UBE2I UBE3A ZMYM2	10 interacting genes: DNPH1 FAM114A2 FCAR PAICS PFDN5 PTPN11 PTPN6 SORBS1 TOM1 UROD
Entrez ID		10606	29992
HPRD ID		01401	05631
Ensembl ID		ENSG00000128050	ENSG00000085514
Uniprot IDs		P22234	Q9UKJ1
PDB IDs		2H31 6YB8 6YB9	3WUZ 3WV0 4NFB 5XO2 5XOF
Enriched GO Terms of Interacting Partners?
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