UBE2V2 and SUV39H2

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
HPRD (two hybrid)

		UBE2V2	SUV39H2
Description		ubiquitin conjugating enzyme E2 V2	SUV39H2 histone lysine methyltransferase
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm UBC13-MMS2 Complex Extracellular Exosome	Chromosome, Centromeric Region Chromatin Nucleus Nucleoplasm
	Molecular Function	Protein Binding	Transcription Cis-regulatory Region Binding Protein Binding Zinc Ion Binding Histone-lysine N-methyltransferase Activity Histone Methyltransferase Activity (H3-K9 Specific) S-adenosyl-L-methionine Binding
	Biological Process	Protein Polyubiquitination DNA Double-strand Break Processing Regulation Of DNA Repair Postreplication Repair Positive Regulation Of Neuron Projection Development Protein Ubiquitination Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Error-free Postreplication DNA Repair Negative Regulation Of Neuron Apoptotic Process Positive Regulation Of DNA Repair Positive Regulation Of Synapse Assembly Protein K63-linked Ubiquitination	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Assembly Or Disassembly Chromatin Remodeling Cell Cycle Cell Differentiation Histone Lysine Methylation Histone H3-K9 Dimethylation Histone H3-K9 Trimethylation Negative Regulation Of Circadian Rhythm Negative Regulation Of Transcription, DNA-templated Rhythmic Process Cellular Response To Hypoxia
Pathways		Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks Nonhomologous End-Joining (NHEJ) Processing of DNA double-strand break ends Formation of Incision Complex in GG-NER G2/M DNA damage checkpoint E3 ubiquitin ligases ubiquitinate target proteins Antigen processing: Ubiquitination & Proteasome degradation	PKMTs methylate histone lysines
Drugs
Diseases
GWAS		Height ( 31562340)	Response to cognitive-behavioural therapy in anxiety disorder ( 31123309)
Interacting Genes		31 interacting genes: BCL10 DZIP3 EGFR HLTF IGSF21 LRIF1 MALT1 MKRN3 MOB4 MUL1 OTUB1 RC3H1 RC3H2 RFFL RNF144A RNF2 RNF8 SHPRH SIAH1 SIAH2 STUB1 SUV39H2 TP53 TRAF2 TRIM5 TRIM54 TRIM63 UBC UBE2N XIAP ZNRF1	41 interacting genes: AKAP9 APPL2 AR BLZF1 C8orf74 CBX7 CDCA4 CEP70 CFAP100 CGGBP1 EWSR1 FAM20C GOLGA6L9 GSTCD ID2 KCTD17 KLF3 KLHDC4 LCA5L LNX1 LRIF1 MAGEA11 MCM3AP MRFAP1 MTF2 MYL12A NME4 ODAD3 PHF19 PNMA1 POLR3F RAB3IP RASSF1 SHC1 SMAD5 SNF8 UBE2V2 WIZ ZNF212 ZNF557 ZNF57
Entrez ID		7336	79723
HPRD ID		04300	07580
Ensembl ID		ENSG00000169139	ENSG00000152455
Uniprot IDs		A0M8W4 Q15819	Q9H5I1
PDB IDs		1J74 1J7D 1ZGU 3VON 4NR3 4NRG 4NRI 4ONL 4ONM 4ONN 4ORH 5AIT 7BBD 7BBF	2R3A 6P0R
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?