TOP2A and TOP2B

  • Number of citations of the paper that reports this interaction (PubMedID 8710863)
  • 9
  • Data Source:
  • HPRD (in vitro)

TOP2A

TOP2B

Description DNA topoisomerase II alpha DNA topoisomerase II beta
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Hip circumference ( 25673412)
  • Hip circumference adjusted for BMI ( 25673412)
  • Neutrophil percentage of white cells ( 32888494)
  • Chronic obstructive pulmonary disease ( 30804561)
Interacting Genes 30 interacting genes: BRCA1 CDK1 COPS5 CSNK2A1 DFFB DHX9 FBXO28 HDAC1 HDAC2 JUN MAPK1 MDM4 PIAS4 PIN1 PLK1 PRKCA PRKCB PRKCG RB1 RNF168 SMURF2 SRPK1 SUMO1 SUMO2 SUMO4 TOP2B TP53 UBE2I XPO1 YWHAE 19 interacting genes: CD3E CSNK2B ERG HDAC1 HDAC2 LAMTOR5 MAPK3 PIAS4 RANBP2 RARA RNF4 SUMO1 SUMO2 TOP2A TOPBP1 TP53 UBE2I XPO1 XRCC5
Entrez ID 7153 7155
HPRD ID 00536 00537
Ensembl ID ENSG00000131747 ENSG00000077097
Uniprot IDs P11388 Q02880 Q59H80
PDB IDs 1LWZ 1ZXM 1ZXN 4FM9 4R1F 5GWK 5NNE 3QX3 4G0U 4G0V 4G0W 4J3N 5GWI 5GWJ 5ZAD 5ZEN 5ZQF 5ZRF
Enriched GO Terms of Interacting Partners?
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