TOP2B and HDAC2

  • Number of citations of the paper that reports this interaction (PubMedID 11062478)
  • 50
  • Data Source:
  • BioGRID (affinity chromatography technology, pull down)

TOP2B

HDAC2

Description DNA topoisomerase II beta histone deacetylase 2
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Chronic obstructive pulmonary disease ( 30804561)
  • Event free survival in diffuse large B-cell lymphoma treated with immunochemotherapy ( 26460308)
  • Metabolite levels ( 23823483)
Interacting Genes 19 interacting genes: CD3E CSNK2B ERG HDAC1 HDAC2 LAMTOR5 MAPK3 PIAS4 RANBP2 RARA RNF4 SUMO1 SUMO2 TOP2A TOPBP1 TP53 UBE2I XPO1 XRCC5 106 interacting genes: ANTXR1 APPL1 ARID4A AURKA BCL11A BRCA1 BRMS1 BRMS1L BUB3 CABIN1 CDC20 CDH1 CDKN1A CDYL CHD3 CHFR CIR1 CSNK2A1 CSNK2A2 CTBP1 CYTOR DAXX DDX20 DMAP1 DNMT1 DNMT3B EED EID2 ERCC6 FKBP3 FOXO3 FTCD FYN GATA3 H2AC1 H2AC20 H2BC21 H3-4 H3C1 HDAC1 HDAC10 HDAC7 HIF1A HIF1AN HOPX HUWE1 IFRD1 IKZF1 IKZF4 ING1 LAMA4 MAD1L1 MBD2 MBD3L2 MEN1 MTA1 MXD1 NACC2 NRIP1 PA2G4 PADI4 PHB2 PHF21A PIAS4 PML PPARD PPP1R8 PTMA RBBP4 RBBP7 RBP1 RCOR1 RELA REV3L RFX5 RUNX3 SALL1 SAP30 SETDB1 SIN3A SMAD2 SMARCA5 SMYD1 SNW1 SP1 SP3 SPEN SS18L1 STAT3 STK25 SUMO2 SUV39H1 SYK TFCP2 THRA THRB TNS4 TOP2A TOP2B TP53 TREML2 USP4 VHL YY1 ZBTB16 ZNF461
Entrez ID 7155 3066
HPRD ID 00537 05521
Ensembl ID ENSG00000077097 ENSG00000196591
Uniprot IDs Q02880 Q59H80 Q92769
PDB IDs 3QX3 4G0U 4G0V 4G0W 4J3N 5GWI 5GWJ 5ZAD 5ZEN 5ZQF 5ZRF 3MAX 4LXZ 4LY1 5IWG 5IX0 6G3O 6WBW 6WBZ 6XDM 6XEB 6XEC 7KBG 7KBH
Enriched GO Terms of Interacting Partners?
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