TOP2A and PIAS4

  • Number of citations of the paper that reports this interaction (PubMedID 33188014)
  • 7
  • Data Source:
  • BioGRID (enzymatic study)

TOP2A

PIAS4

Description DNA topoisomerase II alpha protein inhibitor of activated STAT 4
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Hip circumference ( 25673412)
  • Hip circumference adjusted for BMI ( 25673412)
  • Neutrophil percentage of white cells ( 32888494)
Interacting Genes 30 interacting genes: BRCA1 CDK1 COPS5 CSNK2A1 DFFB DHX9 FBXO28 HDAC1 HDAC2 JUN MAPK1 MDM4 PIAS4 PIN1 PLK1 PRKCA PRKCB PRKCG RB1 RNF168 SMURF2 SRPK1 SUMO1 SUMO2 SUMO4 TOP2B TP53 UBE2I XPO1 YWHAE 88 interacting genes: ACTN1 ALDOA AR AREL1 BARD1 BRCA1 BTAF1 CALCOCO2 CEBPD CHD3 CLK1 COIL ESRRA FTH1 GADD45G HDAC1 HDAC2 HNF4A HNRNPUL1 HTT IL15RA IMMT IMPDH2 IRF3 IRF7 KNTC1 KPNB1 KRT18 LAMP2 LCE1D LEF1 LRIF1 MAGEH1 MAP1LC3A MDC1 MPRIP NEFL NR4A2 OAZ1 OPTN PARP1 PDE4A PDE4D PDE4DIP PHF11 PHGDH PIAS1 PIAS2 PLAG1 PRKCZ PRPF40A PTN RIF1 RPA2 SATB1 SERBP1 SERPINA5 SETDB1 SH3GL3 SKIL SMAD1 SMAD2 SMAD3 SMAD4 SMAD7 SNAI2 SNIP1 SUMO1 SUMO2 SUMO3 TADA3 TCERG1 TICAM1 TOP1 TOP2A TOP2B TP53 TRIM27 TRIM32 TRIM38 UBE2I UBE2K VHL VIM ZBTB34 ZHX1 ZNF512B ZW10
Entrez ID 7153 51588
HPRD ID 00536 06910
Ensembl ID ENSG00000131747 ENSG00000105229
Uniprot IDs P11388 B3KMR4 Q8N2W9
PDB IDs 1LWZ 1ZXM 1ZXN 4FM9 4R1F 5GWK 5NNE
Enriched GO Terms of Interacting Partners?
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