SVIL and BUB1

  • Number of citations of the paper that reports this interaction (PubMedID 20309963)
  • 28
  • Data Source:
  • BioGRID (two hybrid)

SVIL

BUB1

Description supervillin BUB1 mitotic checkpoint serine/threonine kinase
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Age-related cognitive decline (language) (slope of z-scores) ( 30954325)
  • Bone fracture in osteoporosis ( 28580392)
  • Dilated cardiomyopathy ( 33495596)
  • Dilated cardiomyopathy (MTAG) ( 33495596)
  • Estimated glomerular filtration rate ( 31152163)
  • Lung function (FEV1/FVC) ( 28166213)
  • Metabolite levels ( 23823483)
  • Neurofibrillary tangles ( 25188341)
  • Normalized brain volume ( 19010793)
  • Platelet thrombus formation ( 22550155)
  • Plateletcrit ( 32888494)
Interacting Genes 36 interacting genes: AR ATRX BUB1 CENPF DYNLT1 ESR1 FLNA HAX1 HMMR HSP90AA1 ITGB3BP KIF22 KIFC3 KMT2A KRT18 LMNA LMNB2 LUC7L2 MIF4GD MPHOSPH9 MRTFB NME2 NR3C1 ODF2 P2RX7 PAN3 PCNX3 PPARG SH3PXD2A SLAMF7 STARD9 TGFB1I1 TNFAIP1 TRIP6 UXT YWHAG 63 interacting genes: AKT1 ALDOB ANP32B AOPEP AP1B1 AP2B1 AP3B1 AP4B1 APC ARIH2 BAAT BUB3 CCDC180 CDC14B CDC20 CDK1 CDK8 CORO2A CRK CTSV CYLC2 DVL1 EIF4EBP1 FANCC FBP1 FBP2 FBXO7 FRAT2 GALNT12 HDAC1 HEMGN HRAS HSD17B3 IGFBP3 KNL1 LEF1 MAP2K1 MAPK3 MSANTD3 NANS PLK1 PPP2CB PPP3R2 RAE1 RASA1 RDH12 SEC61B SFRP2 SFRP4 SHC1 SMAD1 STX17 SVIL TBC1D2 TDRD7 TGFB1 TMEFF1 TMOD1 TRMO TSTD2 XPA ZNF189 ZNF510
Entrez ID 6840 699
HPRD ID 04992 03907
Ensembl ID ENSG00000197321 ENSG00000169679
Uniprot IDs A0A6I8PIX7 O95425 Q569J5 B4DYG2 O43683
PDB IDs 2K6M 2K6N 2LAH 4A1G 4QPM 4R8Q 5DMZ 6F7B
Enriched GO Terms of Interacting Partners?
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