SVIL and SLAMF7

		SVIL	SLAMF7
Description		supervillin	SLAM family member 7
Image			No pdb structure
GO Annotations	Cellular Component	Podosome Nucleus Cytoplasm Cytosol Plasma Membrane Focal Adhesion Actin Cytoskeleton Midbody Cleavage Furrow Microtubule Minus-end Cell Projection Costamere	Plasma Membrane External Side Of Plasma Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Actin Filament Binding	Identical Protein Binding
	Biological Process	Skeletal Muscle Tissue Development Actin Polymerization Or Depolymerization Positive Regulation Of Cytokinesis Actin Filament Severing Barbed-end Actin Filament Capping	Adaptive Immune Response Cell Adhesion Natural Killer Cell Activation T Cell Activation Natural Killer Cell Mediated Cytotoxicity
Pathways			Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Drugs			Elotuzumab
Diseases
GWAS		Age-related cognitive decline (language) (slope of z-scores) ( 30954325) Bone fracture in osteoporosis ( 28580392) Dilated cardiomyopathy ( 33495596) Dilated cardiomyopathy (MTAG) ( 33495596) Estimated glomerular filtration rate ( 31152163) Lung function (FEV1/FVC) ( 28166213) Metabolite levels ( 23823483) Neurofibrillary tangles ( 25188341) Normalized brain volume ( 19010793) Platelet thrombus formation ( 22550155) Plateletcrit ( 32888494)	Blood protein levels ( 30072576 29875488 28240269) IgM levels ( 28628107) Inflammatory bowel disease ( 23128233) Microalbuminuria ( 26631737) Multiple sclerosis ( 24076602)
Interacting Genes		36 interacting genes: AR ATRX BUB1 CENPF DYNLT1 ESR1 FLNA HAX1 HMMR HSP90AA1 ITGB3BP KIF22 KIFC3 KMT2A KRT18 LMNA LMNB2 LUC7L2 MIF4GD MPHOSPH9 MRTFB NME2 NR3C1 ODF2 P2RX7 PAN3 PCNX3 PPARG SH3PXD2A SLAMF7 STARD9 TGFB1I1 TNFAIP1 TRIP6 UXT YWHAG	11 interacting genes: ADRA2A API5 CLK3 MAK PANK1 PITX2 SH2D1A SVIL THRSP TMOD4 TRIB2
Entrez ID		6840	57823
HPRD ID		04992	09432
Ensembl ID		ENSG00000197321	ENSG00000026751
Uniprot IDs		A0A6I8PIX7 O95425 Q569J5	B4DVL7 B4DW98 Q9NQ25
PDB IDs		2K6M 2K6N
Enriched GO Terms of Interacting Partners?
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