AURKC and CADPS

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		AURKC	CADPS
Description		aurora kinase C	calcium dependent secretion activator
Image
GO Annotations	Cellular Component	Chromosome, Centromeric Region Condensed Chromosome Nucleus Cytoplasm Spindle Spindle Microtubule Midbody Spindle Pole Centrosome Chromosome Passenger Complex Spindle Midzone	Cytosol Presynapse Glutamatergic Synapse Neuronal Dense Core Vesicle Membrane
	Molecular Function	Protein Kinase Activity Protein Serine/threonine/tyrosine Kinase Activity Protein Binding ATP Binding Histone Serine Kinase Activity Protein Serine Kinase Activity	Protein Binding Lipid Binding Protein Kinase Binding Metal Ion Binding
	Biological Process	Protein Phosphorylation Mitotic Spindle Organization Spermatogenesis Attachment Of Spindle Microtubules To Kinetochore Histone Modification Regulation Of Cytokinesis Positive Regulation Of Cytokinesis Histone-serine Phosphorylation Oocyte Development Mitotic Spindle Midzone Assembly Cell Division Meiotic Cell Cycle	Exocytosis Protein Transport Synaptic Vesicle Exocytosis Positive Regulation Of Exocytosis Dense Core Granule Exocytosis
Pathways
Drugs		SNS-314 Fostamatinib	Calcium citrate Calcium Phosphate Calcium phosphate dihydrate
Diseases
GWAS			Adult body size ( 32376654) Autism spectrum disorder ( 30804558) Body size at age 10 ( 32376654) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Breast size ( 22747683 27182965) Cigarettes smoked per day in Schizophrenia ( 33691233) Cognitive decline rate in late mild cognitive impairment ( 26252872) Cortical surface area (MOSTest) ( 32665545) Daytime nap ( 33568662) Economic and political preferences (environmentalism) ( 22566634) Fasting plasma glucose ( 31932636) Hand grip strength ( 29691431) Lung function (FEV1/FVC) ( 30061609) Meat-related diet ( 32066663) Metabolite levels (X-11787) ( 23934736) Obsessive-compulsive symptoms ( 26859814) Optic disc size ( 31809533) Pre-treatment viral load in HIV-1 infection ( 31219150) Processed meat consumption ( 32066663) QT interval (sulfonylurea treatment interaction) ( 27958378) Risk-taking tendency (4-domain principal component model) ( 30643258) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Systolic blood pressure x educational attainment (graduated college) interaction (2df) ( 32372009) Thiopurine-induced leukopenia in inflammatory bowel disease ( 29923122) Trunk fat mass ( 28552196)
Interacting Genes		13 interacting genes: BIRC5 BIRC7 BRCA1 CADPS CENPA H3C1 INCENP LNX1 NEDD4 NEDD4L OTX2 SRPK1 TACC2	49 interacting genes: ACTN3 ANKS1A AURKC C17orf67 C3orf14 CABP5 CCDC120 CCDC185 CCDC70 DMD DNAJC5 DRD2 FAM161A FAM3D FAM90A1 FAM9B FANCL FEZF2 FHIT FOXD2 GADD45GIP1 GPANK1 GSE1 HDAC4 HOXB5 HOXC8 KANK2 KIAA1549 LNX1 LUC7L2 OLIG3 PIP5K1A PNMA5 PRPF18 SDCBP SEC23A SH2D4A SHFL SNTN TCL1A TENT2 TRIM55 TRIM63 TSEN2 TTLL10 USP2 ZFC3H1 ZNF572 ZNF688
Entrez ID		6795	8618
HPRD ID		04605	05236
Ensembl ID		ENSG00000105146	ENSG00000163618
Uniprot IDs		Q9UQB9	F1T0E5 Q9ULU8
PDB IDs		6GR8 6GR9	1WI1
Enriched GO Terms of Interacting Partners?
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