SPTAN1 and KALRN

  • Number of citations of the paper that reports this interaction (PubMedID 17607528)
  • 4
  • Data Source:
  • BioGRID (two hybrid)

SPTAN1

KALRN

Description spectrin alpha, non-erythrocytic 1 kalirin RhoGEF kinase
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Acute graft versus host disease in bone marrow transplantation (donor effect) ( 27595289)
  • Amyotrophic lateral sclerosis ( 26580837)
  • Benign childhood epilepsy with centro-temporal spikes ( 32580138)
  • Childhood ALL/LBL (acute lymphoblastic leukemia/lymphoblastic lymphoma) treatment-related venous thromboembolism ( 32438682)
  • Diffuse large B-cell lymphoma or systemic lupus erythematosus ( 31407831)
  • General cognitive ability ( 29844566)
  • Hematocrit ( 32888494)
  • Heschl's gyrus morphology ( 25130324)
  • Intraocular pressure ( 29617998 29785010 31959993)
  • Liver enzyme levels (gamma-glutamyl transferase) ( 33972514)
  • Longevity (age >99th survival percentile) ( 31413261)
  • Low urine pH ( 30476138)
  • Lymphocyte counts ( 32888494)
  • Marginal zone lymphoma or systemic lupus erythematosus ( 31407831)
  • Mean platelet volume ( 22139419 32888494 27863252)
  • Metabolite levels ( 23823483)
  • Moderate-to-late spontaneous preterm birth ( 31194736)
  • Monocyte count ( 32888494)
  • Myocardial infarction ( 33532862)
  • Neutrophil percentage of white cells ( 32888494)
  • Platelet count ( 32888494 27863252)
  • Platelet distribution width ( 32888494 27863252)
  • Plateletcrit ( 27863252)
  • Post bronchodilator FEV1/FVC ratio ( 26634245)
  • Red cell distribution width ( 32888494)
  • Schizophrenia ( 30285260)
  • Stroke ( 32693751)
  • Systolic blood pressure x dichotomous lifestyle risk score interaction (1df test) ( 32227373)
  • Systolic blood pressure x dichotomous lifestyle risk score interaction (2df test) ( 32227373)
  • Thyroid peroxidase antibody levels ( 24586183)
  • Urine pH measurement ( 30476138)
Interacting Genes 60 interacting genes: ABI1 ABL1 ACP1 ACTA1 ACTB AKIP1 ANK1 C5 CAPN1 CASP3 CASP7 CEP63 CNTRL CREBBP CTNNA1 DDX24 DES EPB41 EPB41L2 EPB42 ERCC4 EVL EXOC1 FANCA FANCC GAP43 GRIA2 GRIN1 GRIN2A GRIN2B GRIN2D KALRN KARS1 MAPK6 NEFL PDE4D PIN4 PLEC PLEKHA5 PRKCB PTEN PTOV1 SHANK1 SHANK3 SLC9A2 SOS1 SPTB SPTBN1 SPTBN2 SPTBN4 SRC STAT1 SUMO2 SYN1 TAF1 TANC1 TES TRAF1 TSSC4 ZNF333 16 interacting genes: ATXN7 CACNA1A CDC5L COIL DISC1 DTNBP1 ENO3 EPHB2 FASLG GFI1B LNX1 NDEL1 PAM SPTAN1 SUMO2 SUMO3
Entrez ID 6709 8997
HPRD ID 01684 06859
Ensembl ID ENSG00000197694 ENSG00000160145
Uniprot IDs A0A384P5S9 Q13813 C9IZQ6 O60229
PDB IDs 2FOT 3F31 3FB2 5FW9 5FWB 5FWC 6ZEH 5QQD 5QQE 5QQF 5QQG 5QQH 5QQI 5QQJ 5QQK 5QQL 5QQM 5QQN 5QU9
Enriched GO Terms of Interacting Partners?
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