KALRN and EPHB2

  • Number of citations of the paper that reports this interaction (PubMedID 12546821)
  • 196
  • Data Source:
  • HPRD (in vitro)

KALRN

EPHB2

Description kalirin RhoGEF kinase EPH receptor B2
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Acute graft versus host disease in bone marrow transplantation (donor effect) ( 27595289)
  • Amyotrophic lateral sclerosis ( 26580837)
  • Benign childhood epilepsy with centro-temporal spikes ( 32580138)
  • Childhood ALL/LBL (acute lymphoblastic leukemia/lymphoblastic lymphoma) treatment-related venous thromboembolism ( 32438682)
  • Diffuse large B-cell lymphoma or systemic lupus erythematosus ( 31407831)
  • General cognitive ability ( 29844566)
  • Hematocrit ( 32888494)
  • Heschl's gyrus morphology ( 25130324)
  • Intraocular pressure ( 29617998 29785010 31959993)
  • Liver enzyme levels (gamma-glutamyl transferase) ( 33972514)
  • Longevity (age >99th survival percentile) ( 31413261)
  • Low urine pH ( 30476138)
  • Lymphocyte counts ( 32888494)
  • Marginal zone lymphoma or systemic lupus erythematosus ( 31407831)
  • Mean platelet volume ( 22139419 32888494 27863252)
  • Metabolite levels ( 23823483)
  • Moderate-to-late spontaneous preterm birth ( 31194736)
  • Monocyte count ( 32888494)
  • Myocardial infarction ( 33532862)
  • Neutrophil percentage of white cells ( 32888494)
  • Platelet count ( 32888494 27863252)
  • Platelet distribution width ( 32888494 27863252)
  • Plateletcrit ( 27863252)
  • Post bronchodilator FEV1/FVC ratio ( 26634245)
  • Red cell distribution width ( 32888494)
  • Schizophrenia ( 30285260)
  • Stroke ( 32693751)
  • Systolic blood pressure x dichotomous lifestyle risk score interaction (1df test) ( 32227373)
  • Systolic blood pressure x dichotomous lifestyle risk score interaction (2df test) ( 32227373)
  • Thyroid peroxidase antibody levels ( 24586183)
  • Urine pH measurement ( 30476138)
Interacting Genes 16 interacting genes: ATXN7 CACNA1A CDC5L COIL DISC1 DTNBP1 ENO3 EPHB2 FASLG GFI1B LNX1 NDEL1 PAM SPTAN1 SUMO2 SUMO3 40 interacting genes: ABL1 ABL2 ACP1 AFDN AQP1 ARHGEF6 CRK EFNA5 EFNB1 EFNB2 ERBB2 ERF FBXO7 FOS GRB2 GRIN1 GRIN2B ITSN1 KALRN KSR1 MMP2 MMP9 MTMR14 NCK1 PICK1 PLCG1 PTK2 RASA1 RNF186 RRAS RYK SDC2 SDCBP SH2D3C SRC SYNJ1 TRIM54 VAV2 VEGFA YES1
Entrez ID 8997 2048
HPRD ID 06859 02997
Ensembl ID ENSG00000160145 ENSG00000133216
Uniprot IDs C9IZQ6 O60229 B4DSE0 P29323 Q4LE53 Q6NVW1
PDB IDs 5QQD 5QQE 5QQF 5QQG 5QQH 5QQI 5QQJ 5QQK 5QQL 5QQM 5QQN 5QU9 1B4F 1F0M 2QBX 3ZFM
Enriched GO Terms of Interacting Partners?
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