SPTAN1 and DDX24

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		SPTAN1	DDX24
Description		spectrin alpha, non-erythrocytic 1	DEAD-box helicase 24
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytosol Plasma Membrane Spectrin Microtubule Cytoskeleton Membrane Cell Junction Cortical Actin Cytoskeleton Specific Granule Lumen Cell Projection Intracellular Membrane-bounded Organelle Extracellular Exosome Extracellular Vesicle Tertiary Granule Lumen	Nucleolus Membrane
	Molecular Function	Actin Binding Structural Constituent Of Cytoskeleton Calcium Ion Binding Protein Binding Calmodulin Binding Cadherin Binding Actin Filament Binding	RNA Binding RNA Helicase Activity ATP Binding ATP Hydrolysis Activity
	Biological Process	Cytoskeleton Organization Actin Cytoskeleton Organization Actin Filament Capping	RNA Metabolic Process
Pathways		Caspase-mediated cleavage of cytoskeletal proteins Nephrin family interactions NCAM signaling for neurite out-growth NCAM signaling for neurite out-growth Interaction between L1 and Ankyrins Interaction between L1 and Ankyrins RAF/MAP kinase cascade Neutrophil degranulation COPI-mediated anterograde transport RHOU GTPase cycle RHOV GTPase cycle Sensory processing of sound by inner hair cells of the cochlea Sensory processing of sound by outer hair cells of the cochlea
Drugs
Diseases
GWAS		Axial length ( 24144296) Body mass index ( 26426971)	Oppositional defiant disorder dimensions in attention-deficit hyperactivity disorder ( 26184070) Post bronchodilator FEV1/FVC ratio ( 26634245)
Interacting Genes		60 interacting genes: ABI1 ABL1 ACP1 ACTA1 ACTB AKIP1 ANK1 C5 CAPN1 CASP3 CASP7 CEP63 CNTRL CREBBP CTNNA1 DDX24 DES EPB41 EPB41L2 EPB42 ERCC4 EVL EXOC1 FANCA FANCC GAP43 GRIA2 GRIN1 GRIN2A GRIN2B GRIN2D KALRN KARS1 MAPK6 NEFL PDE4D PIN4 PLEC PLEKHA5 PRKCB PTEN PTOV1 SHANK1 SHANK3 SLC9A2 SOS1 SPTB SPTBN1 SPTBN2 SPTBN4 SRC STAT1 SUMO2 SYN1 TAF1 TANC1 TES TRAF1 TSSC4 ZNF333	34 interacting genes: BCS1L BRCA1 CSNK2A1 EIF3E EP300 FADD GIT1 GLRA2 HSP90AB1 HSPA5 IDO1 ITGB3BP LMNA MDM2 MKS1 MRPL4 NRXN2 PAFAH1B3 PIN1 POLA2 PRF1 PTEN PTPN23 RAE1 SPACA9 SPTAN1 TERF1 TERF2 TERF2IP TMEM9B TPI1 TRDMT1 UBE2I VDAC3
Entrez ID		6709	57062
HPRD ID		01684	05860
Ensembl ID		ENSG00000197694	ENSG00000089737
Uniprot IDs		A0A384P5S9 Q13813	Q9GZR7
PDB IDs		2FOT 3F31 3FB2 5FW9 5FWB 5FWC 6ZEH
Enriched GO Terms of Interacting Partners?
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