BNIP3L and CYB5B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		BNIP3L	CYB5B
Description		BCL2 interacting protein 3 like	cytochrome b5 type B
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nuclear Envelope Mitochondrion Mitochondrial Outer Membrane Endoplasmic Reticulum Cytosol Integral Component Of Membrane Nuclear Speck Intrinsic Component Of Membrane	Mitochondrial Outer Membrane Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle Nitric-oxide Synthase Complex
	Molecular Function	Protein Binding Lamin Binding Identical Protein Binding Protein Homodimerization Activity	Protein Binding Enzyme Activator Activity Heme Binding Metal Ion Binding Nitrite Reductase (NO-forming) Activity
	Biological Process	Negative Regulation Of Mitochondrial Membrane Potential Positive Regulation Of Macroautophagy Mitochondrial Protein Catabolic Process Positive Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Regulation Of Programmed Cell Death Defense Response To Virus Negative Regulation Of Cell Death Cellular Response To Hypoxia Mitochondrial Outer Membrane Permeabilization Regulation Of Autophagy Of Mitochondrion Regulation Of Protein Targeting To Mitochondrion	Xenobiotic Metabolic Process Nitric Oxide Biosynthetic Process Response To Oxidative Stress Electron Transport Chain Regulation Of Catalytic Activity
Pathways		TP53 Regulates Transcription of Genes Involved in Cytochrome C Release	Phase I - Functionalization of compounds
Drugs			Phenethyl Isothiocyanate
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Cognitive decline rate in late mild cognitive impairment ( 26252872) High light scatter reticulocyte count ( 32888494 27863252) High light scatter reticulocyte percentage of red cells ( 32888494 27863252) Immature fraction of reticulocytes ( 32888494 27863252) Lymphocyte percentage of white cells ( 32888494) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular hemoglobin concentration ( 32888494) Mean corpuscular volume ( 32888494) Red blood cell count ( 32888494) Red cell distribution width ( 32888494 27863252) Schizophrenia ( 28991256 30285260)	Blood osmolality (transformed sodium) ( 28360221) Blood pressure (smoking interaction) ( 25189868) Body mass index ( 26426971) Heel bone mineral density ( 30598549) Homeostasis model assessment of beta-cell function (dietary factor interaction) ( 24204828) Serum uric acid levels ( 30993211 29403010)
Interacting Genes		35 interacting genes: ADIPOQ BCL2 BCL2L1 BNIP3 CAMK1D CASK CLEC7A CLN8 CYB5B DOK5 DUSP3 ECM1 EWSR1 FATE1 GABARAPL1 GABARAPL2 GBP2 GNB5 HTR2B KEAP1 KLHL23 LDLRAD1 LMNA MALL MAP1LC3A NGFR RHEB RINT1 ROBO2 SMCO4 STEAP3 TMEM11 TMEM120B TMPRSS4 TNMD	55 interacting genes: AHNAK2 APP AQP6 B3GNT9 BIK BNIP3L BTNL9 CD33 CD79A CENPT CGRRF1 CLDN7 CLN8 COG8 CPLX4 CREB3 EBP ESRP2 FAM209A FAM210B FNDC9 FRMD3 GJB5 GPR152 IGSF9 KCNK5 KIR2DL3 LMNA MARCHF8 MFF MFSD14B MFSD4B MFSD5 MUC1 NDUFAF2 PDZK1IP1 PHACTR3 PHAF1 PLPP4 REEP4 RETREG3 RPS2P45 SDHAF4 SLC10A6 SLC16A2 SLC39A9 SLC7A6OS STOM STX1A SYT1 TMEM139 TMEM237 TMEM35A TMEM41A TMEM86B
Entrez ID		665	80777
HPRD ID		07288	13106
Ensembl ID		ENSG00000104765	ENSG00000103018
Uniprot IDs		O60238 Q6IBV1	O43169
PDB IDs			3NER
Enriched GO Terms of Interacting Partners?
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