CYB5B and KIR2DL3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		CYB5B	KIR2DL3
Description		cytochrome b5 type B	killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 3
Image
GO Annotations	Cellular Component	Mitochondrial Outer Membrane Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle Nitric-oxide Synthase Complex	Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding Enzyme Activator Activity Heme Binding Metal Ion Binding Nitrite Reductase (NO-forming) Activity	Antigen Binding Protein Binding Signaling Receptor Activity Identical Protein Binding
	Biological Process	Xenobiotic Metabolic Process Nitric Oxide Biosynthetic Process Response To Oxidative Stress Electron Transport Chain Regulation Of Catalytic Activity	Immune Response
Pathways		Phase I - Functionalization of compounds	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Drugs		Phenethyl Isothiocyanate
Diseases
GWAS		Blood osmolality (transformed sodium) ( 28360221) Blood pressure (smoking interaction) ( 25189868) Body mass index ( 26426971) Heel bone mineral density ( 30598549) Homeostasis model assessment of beta-cell function (dietary factor interaction) ( 24204828) Serum uric acid levels ( 30993211 29403010)
Interacting Genes		55 interacting genes: AHNAK2 APP AQP6 B3GNT9 BIK BNIP3L BTNL9 CD33 CD79A CENPT CGRRF1 CLDN7 CLN8 COG8 CPLX4 CREB3 EBP ESRP2 FAM209A FAM210B FNDC9 FRMD3 GJB5 GPR152 IGSF9 KCNK5 KIR2DL3 LMNA MARCHF8 MFF MFSD14B MFSD4B MFSD5 MUC1 NDUFAF2 PDZK1IP1 PHACTR3 PHAF1 PLPP4 REEP4 RETREG3 RPS2P45 SDHAF4 SLC10A6 SLC16A2 SLC39A9 SLC7A6OS STOM STX1A SYT1 TMEM139 TMEM237 TMEM35A TMEM41A TMEM86B	64 interacting genes: ADGRE2 AGTRAP AIG1 ANKRD46 APOA2 APOD APP AQP10 ASGR1 ATP6V0E1 BMP10 BRICD5 BTN2A2 C3orf52 CDIPT CISD2 CLDN19 CLN6 COQ9 CXCL16 CXCL9 CYB5B CYBC1 EMD FAM209A FAM3C FUNDC2 GAST GJA8 GPR108 GPX8 HLA-C IFITM3 INSIG2 ITGAM JAGN1 KTN1 LAT LCK LEUTX LHFPL5 NINJ2 NRM NSG1 OLFM4 PLN PLPPR2 PTPN6 RNF152 RTP2 SEC22B SLC38A7 SMIM1 SNORC THBD TMEM218 TMEM222 TMEM243 TMEM86B TMEM97 TRAF3IP3 UPK1B UPK2 VAMP5
Entrez ID		80777	3804
HPRD ID		13106	10383
Ensembl ID		ENSG00000103018	ENSG00000243772
Uniprot IDs		O43169	E3NZD8 P43628
PDB IDs		3NER	1B6U 6PAG
Enriched GO Terms of Interacting Partners?
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