CYB5B and CGRRF1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		CYB5B	CGRRF1
Description		cytochrome b5 type B	cell growth regulator with ring finger domain 1
Image
GO Annotations	Cellular Component	Mitochondrial Outer Membrane Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle Nitric-oxide Synthase Complex	Nucleoplasm Endoplasmic Reticulum Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding Enzyme Activator Activity Heme Binding Metal Ion Binding Nitrite Reductase (NO-forming) Activity	Protein Binding Metal Ion Binding
	Biological Process	Xenobiotic Metabolic Process Nitric Oxide Biosynthetic Process Response To Oxidative Stress Electron Transport Chain Regulation Of Catalytic Activity	Cell Cycle Negative Regulation Of Cell Population Proliferation Negative Regulation Of Cell Growth
Pathways		Phase I - Functionalization of compounds
Drugs		Phenethyl Isothiocyanate
Diseases
GWAS		Blood osmolality (transformed sodium) ( 28360221) Blood pressure (smoking interaction) ( 25189868) Body mass index ( 26426971) Heel bone mineral density ( 30598549) Homeostasis model assessment of beta-cell function (dietary factor interaction) ( 24204828) Serum uric acid levels ( 30993211 29403010)	Dental caries ( 23259602) Monobrow thickness ( 26926045) Night sleep phenotypes ( 27126917)
Interacting Genes		55 interacting genes: AHNAK2 APP AQP6 B3GNT9 BIK BNIP3L BTNL9 CD33 CD79A CENPT CGRRF1 CLDN7 CLN8 COG8 CPLX4 CREB3 EBP ESRP2 FAM209A FAM210B FNDC9 FRMD3 GJB5 GPR152 IGSF9 KCNK5 KIR2DL3 LMNA MARCHF8 MFF MFSD14B MFSD4B MFSD5 MUC1 NDUFAF2 PDZK1IP1 PHACTR3 PHAF1 PLPP4 REEP4 RETREG3 RPS2P45 SDHAF4 SLC10A6 SLC16A2 SLC39A9 SLC7A6OS STOM STX1A SYT1 TMEM139 TMEM237 TMEM35A TMEM41A TMEM86B	32 interacting genes: AGR3 BET1 CD72 CDIPT CREB3 CYB5B FAM241B FAXDC2 FFAR2 GPR151 GPR152 JAGN1 KLRC1 LAPTM4B LNPEP MARCHF5 MTIF3 PEX10 PGAP2 RHBDD1 SCAMP4 SLC30A3 SLC30A8 SUSD3 TMEM140 TMEM187 TMEM31 TMEM97 TPRG1 UBE2U YIPF6 ZFPL1
Entrez ID		80777	10668
HPRD ID		13106	09366
Ensembl ID		ENSG00000103018	ENSG00000100532
Uniprot IDs		O43169	Q99675
PDB IDs		3NER	2EA5
Enriched GO Terms of Interacting Partners?
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