SLC15A2 and PDZK1

Number of citations of the paper that reports this interaction (PubMedID 15553237)
13

Data Source:
HPRD (in vivo, in vitro, two hybrid)

		SLC15A2	PDZK1
Description		solute carrier family 15 member 2	PDZ domain containing 1
Image
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Apical Plasma Membrane Spanning Component Of Plasma Membrane Extracellular Exosome Spanning Component Of Membrane	Plasma Membrane Brush Border Apical Plasma Membrane Brush Border Membrane Microvillus Membrane Membrane Raft Extracellular Exosome
	Molecular Function	Protein Binding Peptide:proton Symporter Activity Dipeptide Transmembrane Transporter Activity	Scavenger Receptor Binding Protein Binding PDZ Domain Binding Protein-membrane Adaptor Activity Protein-containing Complex Binding
	Biological Process	Ion Transport Protein Transport Peptidoglycan Transport Xenobiotic Transport Dipeptide Transport Innate Immune Response Renal Absorption Regulation Of Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Dipeptide Import Across Plasma Membrane Transport Across Blood-brain Barrier Proton Transmembrane Transport Xenobiotic Detoxification By Transmembrane Export Across The Plasma Membrane	Carnitine Transport Positive Regulation Of Ion Transmembrane Transporter Activity Regulation Of Anion Transport Protein Localization To Plasma Membrane Positive Regulation Of Protein Targeting To Membrane Positive Regulation Of Cation Transmembrane Transport Positive Regulation Of Protein Localization To Membrane Xenobiotic Detoxification By Transmembrane Export Across The Plasma Membrane
Pathways		Proton/oligopeptide cotransporters
Drugs		Ampicillin Cefotaxime Oxacillin Benzylpenicillin
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29083406) Estimated glomerular filtration rate ( 31152163 31015462 31451708 30604766) Glomerular filtration rate ( 29403010) Hematocrit ( 32888494) Hemoglobin ( 32888494) Hemoglobin levels ( 32327693) Multiple sclerosis ( 21833088) Multiple sclerosis and HDL levels (pleiotropy) ( 26920376) Platelet count ( 32888494) Plateletcrit ( 32888494)	Contrast sensitivity ( 24152035) Gout ( 33832965 32238385) Serum uric acid levels ( 30993211) Urate levels ( 31985003 20884846 31578528 23263486) Urate levels in overweight individuals ( 25811787) Uric acid levels ( 19503597)
Interacting Genes		26 interacting genes: ADAM12 ANKS1A AQP1 C11orf87 CHRD ENKD1 KLHL38 KPRP KRT34 KRTAP12-2 KRTAP12-3 KRTAP15-1 KRTAP26-1 KRTAP6-3 LMO4 NTAQ1 OTX1 PDZD3 PDZK1 PITX1 PLSCR4 SMARCC1 TENT5B TLX3 VENTX WWOX	31 interacting genes: ABCA1 ABCC2 ABCC4 ACE2 AKAP10 APP CFTR CLCN3 CRHR1 FARP2 GFAP PDZK1IP1 PEX5 RPS6KA1 SCARB1 SLC13A1 SLC15A2 SLC17A1 SLC22A11 SLC22A12 SLC22A4 SLC22A5 SLC26A6 SLC34A1 SLC9A3 SLC9A3R1 SLC9A3R2 SLCO1A2 SLK SSTR5 UBE2I
Entrez ID		6565	5174
HPRD ID		09088	04829
Ensembl ID		ENSG00000163406	ENSG00000174827
Uniprot IDs		Q16348	Q5T2W1
PDB IDs		6EZI	2EEI 2EEJ 2VSP 3TMH 4Q2P 6EZI
Enriched GO Terms of Interacting Partners?
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