CRTC3 and RGMA

		CRTC3	RGMA
Description		CREB regulated transcription coactivator 3	repulsive guidance molecule BMP co-receptor a
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol	Endoplasmic Reticulum Plasma Membrane Cell Surface Anchored Component Of Membrane Neuron Projection
	Molecular Function	Protein Binding CAMP Response Element Binding Protein Binding	Protein Binding Coreceptor Activity Transferrin Receptor Binding
	Biological Process	Positive Regulation Of CREB Transcription Factor Activity Macrophage Activation Negative Regulation Of CAMP-mediated Signaling Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Lipid Catabolic Process Protein Homotetramerization Energy Homeostasis	Neural Tube Closure Positive Regulation Of Neuron Projection Development BMP Signaling Pathway Regulation Of BMP Signaling Pathway Neuron Projection Development Positive Regulation Of GTPase Activity Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Collateral Sprouting Negative Regulation Of Axon Regeneration Positive Regulation Of Membrane Protein Ectodomain Proteolysis Negative Regulation Of Receptor Binding
Pathways		Transcriptional activation of mitochondrial biogenesis Circadian Clock Heme signaling	Netrin-1 signaling
Drugs
Diseases
GWAS		Apolipoprotein B levels ( 32203549) Chromium levels ( 26025379) Chronic postoperative pain ( 31903573) Colorectal cancer ( 29228715) Daytime sleep phenotypes ( 27126917) Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494) Gastroesophageal reflux disease ( 27485664) Heel bone mineral density ( 28869591) Inflammatory bowel disease ( 28067908 23128233) Information processing speed ( 21130836) Male-pattern baldness ( 28196072) Offspring birth weight ( 31043758) Response to exercise (triglyceride level interaction) ( 26491034) Ulcerative colitis ( 28067908)	Blood protein levels ( 30072576 29875488) Copper levels ( 26025379) HDL cholesterol levels x short total sleep time interaction (2df test) ( 31719535) Heel bone mineral density ( 30598549) Metabolite levels ( 23823483) Opioid dependence ( 29478698) Overweight status ( 25133637) Periodontitis (CDC/AAP) ( 24024966) Refractive error ( 32231278) Response to angiotensin II receptor blocker therapy (opposite direction w/ diuretic therapy) ( 22566498) Type 1 diabetes nephropathy ( 23028342) Type 2 diabetes ( 32499647)
Interacting Genes		12 interacting genes: AEN C15orf32 CA13 HAPLN3 KLHL12 RCCD1 RGMA SIK2 TICRR UNC45A WDR93 YWHAG	5 interacting genes: CRTC3 PPP1R16A SGSM2 TERF2IP TP53BP2
Entrez ID		64784	56963
HPRD ID		13384	09560
Ensembl ID		ENSG00000140577	ENSG00000182175
Uniprot IDs		Q6UUV7 Q8TEF4	A0A0A0MTQ4 Q96B86
PDB IDs			4UHY 6Z3G
Enriched GO Terms of Interacting Partners?
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