NUCKS1 and AK5

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		NUCKS1	AK5
Description		nuclear casein kinase and cyclin dependent kinase substrate 1	adenylate kinase 5
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Nucleolus Cytoplasm	Cytoplasm Cytosol Centriolar Satellite
	Molecular Function	Chromatin Binding Double-stranded DNA Binding Single-stranded DNA Binding Transcription Coactivator Activity RNA Binding Transcription Factor Binding	Adenylate Kinase Activity Nucleoside Diphosphate Kinase Activity ATP Binding
	Biological Process	Double-strand Break Repair Via Homologous Recombination Cellular Glucose Homeostasis Regulation Of DNA Replication Chromatin Organization Regulation Of Transcription By RNA Polymerase II Release From Viral Latency Replication Fork Processing Gene Conversion Interstrand Cross-link Repair Positive Regulation By Host Of Viral Transcription Positive Regulation By Host Of Viral Genome Replication Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Insulin Receptor Signaling Pathway Positive Regulation Of Insulin Receptor Signaling Pathway Regulation Of DNA Strand Elongation Cellular Response To X-ray Modulation By Host Of RNA Binding By Virus Modulation By Host Of Viral RNA-binding Transcription Factor Activity	Nucleoside Diphosphate Phosphorylation ADP Biosynthetic Process DADP Biosynthetic Process Nucleoside Triphosphate Biosynthetic Process Pyrimidine Ribonucleotide Biosynthetic Process ATP Metabolic Process Nucleoside Monophosphate Phosphorylation
Pathways			Interconversion of nucleotide di- and triphosphates
Drugs
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) Atrial fibrillation ( 30061737 29892015) Body mass index ( 28892062) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Free thyroxine concentration ( 30367059) HDL cholesterol levels ( 32203549) Menarche (age at onset) ( 25231870) Parkinson's disease ( 19915575 19915576 25064009 32201043 27182965 28892059) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892) Posterior thalamic nuclei volume ( 34006833) Prostate-specific antigen levels ( 25434496 23269536) Pubertal anthropometrics ( 23449627) QT interval ( 24952745) Serum alkaline phosphatase levels ( 33547301) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Weight ( 28552196)	Body mass index ( 25673413) Chronotype ( 26955885 30696823 27494321) Eosinophil percentage of white cells ( 27863252) Estimated glomerular filtration rate ( 31152163) High light scatter reticulocyte percentage of red cells ( 32888494) Household income (MTAG) ( 31844048) Immature fraction of reticulocytes ( 32888494) Lung adenocarcinoma ( 28604730) Lung cancer ( 28604730) Lung cancer in ever smokers ( 28604730) Mean reticulocyte volume ( 32888494) Morning person ( 30696823) Morning vs. evening chronotype ( 26955885 26835600 27494321) Sleep traits (multi-trait analysis) ( 27992416) Type 2 diabetes (age of onset) ( 28060188) Urinary albumin excretion ( 30220432) Urinary albumin-to-creatinine ratio ( 31630189)
Interacting Genes		4 interacting genes: AK5 DOCK9 GLP1R MDM2	7 interacting genes: C7orf26 CPNE6 NUCKS1 RNF114 STRN4 TRIM46 UGDH
Entrez ID		64710	26289
HPRD ID		11406	10472
Ensembl ID		ENSG00000069275	ENSG00000154027
Uniprot IDs		Q9H1E3	Q9Y6K8
PDB IDs			2BWJ
Enriched GO Terms of Interacting Partners?
Tagcloud ?
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