AK5 and UGDH

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		AK5	UGDH
Description		adenylate kinase 5	UDP-glucose 6-dehydrogenase
Image
GO Annotations	Cellular Component	Cytoplasm Cytosol Centriolar Satellite	Nucleus Nucleoplasm Cytosol Extracellular Exosome
	Molecular Function	Adenylate Kinase Activity Nucleoside Diphosphate Kinase Activity ATP Binding	UDP-glucose 6-dehydrogenase Activity Identical Protein Binding NAD Binding
	Biological Process	Nucleoside Diphosphate Phosphorylation ADP Biosynthetic Process DADP Biosynthetic Process Nucleoside Triphosphate Biosynthetic Process Pyrimidine Ribonucleotide Biosynthetic Process ATP Metabolic Process Nucleoside Monophosphate Phosphorylation	Gastrulation With Mouth Forming Second Carbohydrate Metabolic Process Glycosaminoglycan Biosynthetic Process UDP-glucuronate Biosynthetic Process Heparan Sulfate Proteoglycan Biosynthetic Process Chondroitin Sulfate Biosynthetic Process Protein Hexamerization Neuron Development
Pathways		Interconversion of nucleotide di- and triphosphates	Formation of the active cofactor, UDP-glucuronate
Drugs			NADH Copper
Diseases
GWAS		Body mass index ( 25673413) Chronotype ( 26955885 30696823 27494321) Eosinophil percentage of white cells ( 27863252) Estimated glomerular filtration rate ( 31152163) High light scatter reticulocyte percentage of red cells ( 32888494) Household income (MTAG) ( 31844048) Immature fraction of reticulocytes ( 32888494) Lung adenocarcinoma ( 28604730) Lung cancer ( 28604730) Lung cancer in ever smokers ( 28604730) Mean reticulocyte volume ( 32888494) Morning person ( 30696823) Morning vs. evening chronotype ( 26955885 26835600 27494321) Sleep traits (multi-trait analysis) ( 27992416) Type 2 diabetes (age of onset) ( 28060188) Urinary albumin excretion ( 30220432) Urinary albumin-to-creatinine ratio ( 31630189)	Haemorrhoidal disease ( 33888516) Response to tofacitinib treatment in psoriasis (herpes zoster) ( 33455090) Response to tofacitinib treatment in psoriasis (herpes zoster)(time to event) ( 33455090)
Interacting Genes		7 interacting genes: C7orf26 CPNE6 NUCKS1 RNF114 STRN4 TRIM46 UGDH	5 interacting genes: AK5 CDC42 ITGB1BP2 RAD51 UGT1A1
Entrez ID		26289	7358
HPRD ID		10472	04535
Ensembl ID		ENSG00000154027	ENSG00000109814
Uniprot IDs		Q9Y6K8	O60701
PDB IDs		2BWJ	2Q3E 2QG4 3ITK 3KHU 3PRJ 3PTZ 3TDK 3TF5 4EDF 4RJT 5TJH 5VR8 5W4X 6C4J 6C4K 6C58 6C5A 6C5Z
Enriched GO Terms of Interacting Partners?
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