AK5 and RNF114

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		AK5	RNF114
Description		adenylate kinase 5	ring finger protein 114
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Centriolar Satellite	Nucleus Cytosol Plasma Membrane
	Molecular Function	Adenylate Kinase Activity Nucleoside Diphosphate Kinase Activity ATP Binding	Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Nucleoside Diphosphate Phosphorylation ADP Biosynthetic Process DADP Biosynthetic Process Nucleoside Triphosphate Biosynthetic Process Pyrimidine Ribonucleotide Biosynthetic Process ATP Metabolic Process Nucleoside Monophosphate Phosphorylation	Protein Polyubiquitination Ubiquitin-dependent Protein Catabolic Process Spermatogenesis Cell Differentiation
Pathways		Interconversion of nucleotide di- and triphosphates	Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Body mass index ( 25673413) Chronotype ( 26955885 30696823 27494321) Eosinophil percentage of white cells ( 27863252) Estimated glomerular filtration rate ( 31152163) High light scatter reticulocyte percentage of red cells ( 32888494) Household income (MTAG) ( 31844048) Immature fraction of reticulocytes ( 32888494) Lung adenocarcinoma ( 28604730) Lung cancer ( 28604730) Lung cancer in ever smokers ( 28604730) Mean reticulocyte volume ( 32888494) Morning person ( 30696823) Morning vs. evening chronotype ( 26955885 26835600 27494321) Sleep traits (multi-trait analysis) ( 27992416) Type 2 diabetes (age of onset) ( 28060188) Urinary albumin excretion ( 30220432) Urinary albumin-to-creatinine ratio ( 31630189)	Gut microbiota (beta diversity) ( 27723756) Inflammatory skin disease ( 25574825) Psoriasis ( 25903422 20953189 25574825 23143594) Psoriasis vulgaris ( 26626624) Systemic lupus erythematosus ( 24871463)
Interacting Genes		7 interacting genes: C7orf26 CPNE6 NUCKS1 RNF114 STRN4 TRIM46 UGDH	29 interacting genes: AK5 BMI1 EVI2A MAP3K1 MAPK3 RNF38 RPSA SMURF1 TRAF4 TRAF6 TRAIP TRIM52 TRIM55 UBC UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2DNL UBE2E1 UBE2E2 UBE2E3 UBE2H UBE2K UBE2L3 UBE2U UBE2W UEVLD XAF1
Entrez ID		26289	55905
HPRD ID		10472	10329
Ensembl ID		ENSG00000154027	ENSG00000124226
Uniprot IDs		Q9Y6K8	Q9Y508
PDB IDs		2BWJ
Enriched GO Terms of Interacting Partners?
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