TEKT3 and PLEKHG4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TEKT3	PLEKHG4
Description		tektin 3	pleckstrin homology and RhoGEF domain containing G4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Acrosomal Membrane Outer Acrosomal Membrane Nucleus Microtubule Cytoskeleton Sperm Flagellum Extracellular Exosome	Cytosol
	Molecular Function	Molecular_function Protein Binding	Guanyl-nucleotide Exchange Factor Activity Protein Binding
	Biological Process	Flagellated Sperm Motility Cilium Assembly Cilium Movement Involved In Cell Motility Regulation Of Brood Size	Regulation Of Catalytic Activity Regulation Of Small GTPase Mediated Signal Transduction
Pathways			RHOA GTPase cycle CDC42 GTPase cycle RAC1 GTPase cycle
Drugs
Diseases
GWAS		Preterm birth (maternal effect) ( 28877031) Resting heart rate ( 27798624)	Blood protein levels ( 29875488 28240269) Body shape index ( 34021172) Heel bone mineral density ( 28869591) High density lipoprotein cholesterol levels ( 33339817) Refractive error ( 32231278) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		33 interacting genes: AJUBA ARID5A ASPG ATN1 CALCOCO2 CNOT2 DDI1 GORASP2 HNRNPH1 IKZF3 INSC KRT34 KRTAP15-1 KRTAP19-5 KRTAP26-1 KRTAP3-1 KRTAP6-1 KRTAP6-2 KRTAP8-1 LASP1 LMO2 METTL27 OIP5 PLAGL2 PLEKHG4 RAMAC RFX6 SPAG8 TEX45 TNS2 TRAF2 TRIB3 WWOX	66 interacting genes: A1CF ARHGEF5 ARMC7 BEX2 CCDC120 CCDC187 CDC42 CDKN2C CHIC2 COIL DCUN1D5 DPPA3 DTX2 DUSP13 FAM161A FGD2 GATA3 GCM2 GSTZ1 HCK HOXB9 HOXC8 KRT3 KRT75 MALSU1 MATR3 MDFI METAP1 MSRB3 MTA1 MYEF2 MYOZ1 NATD1 OTX1 PFKFB1 PKP2 PLA2G15 PPP1R32 PRPF18 PRPF31 PSMB1 RHOA RIN1 SAXO1 SETD5 SH2D4A SHISA6 SIX1 SMCP SMG9 TBC1D22B TBX18 TEKT3 TENT5D TFAP2D TFG TRIM55 TRIM63 TSSK3 TTC23 USP2 VPS37C ZCCHC14 ZNF148 ZNF319 ZNF648
Entrez ID		64518	25894
HPRD ID		18173	10890
Ensembl ID		ENSG00000125409	ENSG00000196155
Uniprot IDs		Q9BXF9	A0A024R6X4 Q58EX7
PDB IDs
Enriched GO Terms of Interacting Partners?
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