TEKT3 and RFX6

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TEKT3	RFX6
Description		tektin 3	regulatory factor X6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Acrosomal Membrane Outer Acrosomal Membrane Nucleus Microtubule Cytoskeleton Sperm Flagellum Extracellular Exosome	Chromatin Nucleus
	Molecular Function	Molecular_function Protein Binding	Transcription Cis-regulatory Region Binding RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding
	Biological Process	Flagellated Sperm Motility Cilium Assembly Cilium Movement Involved In Cell Motility Regulation Of Brood Size	Type B Pancreatic Cell Differentiation Pancreatic A Cell Differentiation Pancreatic D Cell Differentiation Regulation Of Transcription By RNA Polymerase II Endocrine Pancreas Development Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Glucose Homeostasis Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Insulin Secretion Pancreatic Epsilon Cell Differentiation
Pathways			Regulation of gene expression in beta cells
Drugs
Diseases
GWAS		Preterm birth (maternal effect) ( 28877031) Resting heart rate ( 27798624)	Apolipoprotein A1 levels ( 32203549) Aspartate aminotransferase levels ( 33547301) Chronic obstructive pulmonary disease ( 30804561) Creatine kinase levels ( 29403010) Diastolic blood pressure ( 27841878) Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494) Fasting glucose ( 34059833) Height ( 31562340) Inflammatory bowel disease ( 27569725) Lung cancer ( 28604730) Neutrophil percentage of granulocytes ( 27863252) Offspring birth weight ( 31043758) Prostate cancer ( 20676098 31562322 26443449) Serum total protein level ( 29403010) Type 2 diabetes or prostate cancer (pleiotropy) ( 33290408)
Interacting Genes		33 interacting genes: AJUBA ARID5A ASPG ATN1 CALCOCO2 CNOT2 DDI1 GORASP2 HNRNPH1 IKZF3 INSC KRT34 KRTAP15-1 KRTAP19-5 KRTAP26-1 KRTAP3-1 KRTAP6-1 KRTAP6-2 KRTAP8-1 LASP1 LMO2 METTL27 OIP5 PLAGL2 PLEKHG4 RAMAC RFX6 SPAG8 TEX45 TNS2 TRAF2 TRIB3 WWOX	41 interacting genes: AGXT ARNT2 CATSPER1 CCNK CSTF2 CYFIP1 DGCR6 DMRT3 DTX2 DUSP21 ESR2 FHL3 FRS3 HGS KCTD9 KIF1A LGALS4 LMO3 MEMO1 NEDD9 PATZ1 PITX1 PLEKHN1 PPP1R32 PRKAA1 PRKAA2 RFX2 RFX3 RIPK3 SNRPB SNRPC SS18L1 STK16 TEKT3 TEKT4 TENT5B TLE5 USP2 VPS37C ZMYND19 ZNF688
Entrez ID		64518	222546
HPRD ID		18173	11490
Ensembl ID		ENSG00000125409	ENSG00000185002
Uniprot IDs		Q9BXF9	Q8HWS3
PDB IDs
Enriched GO Terms of Interacting Partners?
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