SGK1 and PDPK1

  • Number of citations of the paper that reports this interaction (PubMedID 10191262)
  • 179
  • Data Source:
  • BioGRID (pull down, pull down, enzymatic study)
  • HPRD (in vitro, in vivo)

SGK1

PDPK1

Description serum/glucocorticoid regulated kinase 1 3-phosphoinositide dependent protein kinase 1
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Blond vs. brown/black hair color ( 30531825)
  • Body mass index (smoking years interaction) ( 23192594)
  • Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)
  • Immune reponse to smallpox (secreted IFN-alpha) ( 22610502)
  • Parkinson's disease motor subtype (tremor to postural instability/gait difficulty score ratio) ( 33987465)
  • Pelvic organ prolapse ( 26545240)
  • Pelvic organ prolapse (moderate/severe) ( 26545240)
  • Refractive error ( 32231278)
  • Schizophrenia (inflammation and infection response interaction) ( 25781172)
  • Systolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)
  • Hip circumference adjusted for BMI ( 34021172)
Interacting Genes 37 interacting genes: ASPG BRAF CAMKK1 CARHSP1 CDKN1B CETN3 CREB1 FANCA FOXO3 GADD45G GSK3A GSK3B IKBKG KCNJ1 KPNA2 MAGEA1 MAL2 MAPK7 MAPKAP1 MLLT3 NDRG1 NDRG4 NEDD4 NEDD4L NEK6 PDK1 PDK2 PDPK1 PIK3CA PIN1 PPP2CA RABAC1 RICTOR SLC1A3 SLC9A3R2 TMEM184C UBC 63 interacting genes: AKT1 AKT2 AKT3 AKTIP APBB3 APP BLMH CARD11 CDAN1 CSK DDIT4 GIT1 HSP90AA1 ILK IRS1 ITGB3 KATNBL1 LUC7L2 MAPK8 MTOR PAK1 PEA15 PHAX PIK3C3 PKD1 PKN1 PKN2 PNO1 POLDIP2 PRKACA PRKCB PRKCD PRKCE PRKCI PRKCZ PRSS23 PRXL2B PTK2B PXN RALGDS RPS6KA1 RPS6KA3 RPS6KB1 RPS6KB2 SBF1 SGK1 SGK2 SGK3 SLC9A3R2 SMARCB1 SOCS3 SRC SRPK1 STRAP TCAP UBE2I WDCP XPO7 XRCC6 YWHAH YWHAQ ZC3HC1 ZNF133
Entrez ID 6446 5170
HPRD ID 04264 05556
Ensembl ID ENSG00000118515 ENSG00000140992
Uniprot IDs B7Z325 E9PR89 O00141 O15530
PDB IDs 2R5T 3HDM 3HDN 1H1W 1OKY 1OKZ 1UU3 1UU7 1UU8 1UU9 1UVR 1W1D 1W1G 1W1H 1Z5M 2BIY 2PE0 2PE1 2PE2 2R7B 2VKI 2XCH 2XCK 3H9O 3HRC 3HRF 3ION 3IOP 3NAX 3NAY 3NUN 3NUS 3NUU 3NUY 3ORX 3ORZ 3OTU 3PWY 3QC4 3QCQ 3QCS 3QCX 3QCY 3QD0 3QD3 3QD4 3RCJ 3RWP 3RWQ 3SC1 4A06 4A07 4AW0 4AW1 4CT1 4CT2 4RQK 4RQV 4RRV 4XX9 5ACK 5HKM 5HNG 5HO7 5HO8 5LVL 5LVM 5LVN 5LVO 5LVP 5MRD 6WJQ
Enriched GO Terms of Interacting Partners?
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