SGK1 and PDK2

  • Number of citations of the paper that reports this interaction (PubMedID 10191262)
  • 179
  • Data Source:
  • HPRD (in vitro)

SGK1

PDK2

Description serum/glucocorticoid regulated kinase 1 pyruvate dehydrogenase kinase 2
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Blond vs. brown/black hair color ( 30531825)
  • Body mass index (smoking years interaction) ( 23192594)
  • Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)
  • Immune reponse to smallpox (secreted IFN-alpha) ( 22610502)
  • Parkinson's disease motor subtype (tremor to postural instability/gait difficulty score ratio) ( 33987465)
  • Pelvic organ prolapse ( 26545240)
  • Pelvic organ prolapse (moderate/severe) ( 26545240)
  • Refractive error ( 32231278)
  • Schizophrenia (inflammation and infection response interaction) ( 25781172)
  • Systolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)
Interacting Genes 37 interacting genes: ASPG BRAF CAMKK1 CARHSP1 CDKN1B CETN3 CREB1 FANCA FOXO3 GADD45G GSK3A GSK3B IKBKG KCNJ1 KPNA2 MAGEA1 MAL2 MAPK7 MAPKAP1 MLLT3 NDRG1 NDRG4 NEDD4 NEDD4L NEK6 PDK1 PDK2 PDPK1 PIK3CA PIN1 PPP2CA RABAC1 RICTOR SLC1A3 SLC9A3R2 TMEM184C UBC 11 interacting genes: AKT1 DLAT HIC2 HTT ISOC2 MAP3K8 PDHA1 PDHX PDK1 SGK1 VSIG4
Entrez ID 6446 5164
HPRD ID 04264 03955
Ensembl ID ENSG00000118515 ENSG00000005882
Uniprot IDs B7Z325 E9PR89 O00141 Q15119
PDB IDs 2R5T 3HDM 3HDN 2BTZ 2BU2 2BU5 2BU6 2BU7 2BU8 4MP2 4MP7 4MPC 4MPE 4MPN 4V25 4V26 5J6A 5J71 5M4K 5M4M 5M4N 5M4P 6LIL 6LIN 6LIO 6TMP 6TMQ 6TMZ 6TN0 6TN2
Enriched GO Terms of Interacting Partners?
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