AZI2 and RNF31

Number of citations of the paper that reports this interaction (PubMedID 21903422)
143

Data Source:
BioGRID (pull down)

		AZI2	RNF31
Description		5-azacytidine induced 2	ring finger protein 31
Image
GO Annotations	Cellular Component	Cytoplasm	Cytosol Cytoplasmic Side Of Plasma Membrane CD40 Receptor Complex LUBAC Complex
	Molecular Function	Protein Binding	Ubiquitin-protein Transferase Activity Protein Binding Ubiquitin Protein Ligase Binding K48-linked Polyubiquitin Modification-dependent Protein Binding Identical Protein Binding Ubiquitin Binding Metal Ion Binding Ubiquitin Protein Ligase Activity K63-linked Polyubiquitin Modification-dependent Protein Binding Linear Polyubiquitin Binding
	Biological Process	Mitotic Cell Cycle I-kappaB Kinase/NF-kappaB Signaling T Cell Activation Dendritic Cell Proliferation Dendritic Cell Differentiation	Protein Polyubiquitination CD40 Signaling Pathway Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling T Cell Receptor Signaling Pathway Positive Regulation Of NF-kappaB Transcription Factor Activity Protein Linear Polyubiquitination Positive Regulation Of Protein Targeting To Mitochondrion
Pathways			Regulation of TNFR1 signaling TNFR1-induced NFkappaB signaling pathway
Drugs
Diseases
GWAS		Cognitive decline (age-related) ( 28078323)	Suicide behavior ( 26079190)
Interacting Genes		13 interacting genes: APBA3 FAM107A IKBKE MIB1 MTPAP N4BP1 RB1CC1 RNF31 TAX1BP1 TBK1 TICAM1 TRAF3 TXLNA	51 interacting genes: ATG13 ATN1 ATXN1 ATXN7 AZI2 CASP1 CASP6 CASP8 CCDC24 CDC34 GFI1B HDAC6 IKBKG KIF1A KRTAP9-2 NOS3 NR0B1 NR0B2 PITX1 PRKCA RBCK1 SEPTIN2 SMAD3 SNRPC SOCS3 SPATA2 STK4 TLE5 TRAF1 TRAF6 TRIM25 TSSC4 UBC UBE2C UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2K UBE2L3 UBE2O UBE2Q1 UBE2Q2 UBE2R2 UBE2T UBE2W VASN VDAC1
Entrez ID		64343	55072
HPRD ID		10577	11516
Ensembl ID		ENSG00000163512	ENSG00000092098
Uniprot IDs		Q9H6S1	Q96EP0
PDB IDs		5EP6 5Z7G 5Z7L	2CT7 4DBG 4JUY 4LJO 4LJP 4LJQ 4OWF 4OYJ 4OYK 4P09 4P0A 4P0B 5EDV 5LJN 5X0W 6GZY 6KC5 6KC6 6SC5 6SC6 6SC7 6SC8 6SC9
Enriched GO Terms of Interacting Partners?
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